Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23051111 | 0.87 | HDAC3 (0.60) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23051157 | 0.86 | HTT (0.46) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24497075 | 0.85 | SIGMAR1 (0.50) | MEN1KMT2A | |
| SCHEMBL23051155 | 0.83 | ATM (0.44) | HTTLMNAMTNR1AMTNR1BMEN1 | |
| SCHEMBL24497227 | 0.83 | LMNA (0.58) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24497080 | 0.83 | HTT (0.47) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23051139 | 0.80 | MEN1 (0.43) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23051105 | 0.78 | CACNA1G (0.41) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21249722 | 0.77 | ALDH1A1 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL23051109 | 0.77 | HPGD (0.48) | LMNAKDM4EMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041583-A1 | COMPOUNDS TO IDENTIFY BETA-LACTAMASES, AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-03-04 | — | — | WO | disclosed |