Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23051105 | 0.83 | CACNA1G (0.41) | L3MBTL1LTA4HMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL21249722 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL23051155 | 0.82 | ATM (0.44) | MEN1KMT2AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL24497081 | 0.81 | POLB (0.41) | MEN1KMT2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL24497225 | 0.81 | KDM4E (0.44) | MTNR1AMTNR1BALDH1A1KDM4ECYP1A2 | |
| SCHEMBL14723177 | 0.81 | L3MBTL1 (0.50) | MEN1KMT2AL3MBTL1LTA4HALDH1A1 | |
| SCHEMBL3083874 | 0.80 | ALDH1A1 (0.52) | L3MBTL1MTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL24497074 | 0.80 | POLB (0.37) | MEN1KMT2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL23051110 | 0.80 | HTT (0.47) | MEN1KMT2AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL10504820 | 0.79 | CES2 (0.52) | MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041583-A1 | COMPOUNDS TO IDENTIFY BETA-LACTAMASES, AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-03-04 | — | — | WO | disclosed |