Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | FABP3 | P05413 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889001 | 0.86 | SMN1; SMN2 (0.58) | L3MBTL1ALDH1A1TDP1GAASMN1; SMN2 | |
| SCHEMBL17611091 | 0.79 | TPSAB1 (0.50) | L3MBTL1ALDH1A1TDP1GAASMN1; SMN2 | |
| SCHEMBL15773800 | 0.79 | NR1H2 (0.46) | NR3C1TDP1F10 | |
| SCHEMBL13797634 | 0.78 | NPY5R (0.48) | NR3C1ALDH1A1LMNA | |
| SCHEMBL5188624 | 0.77 | HDAC1 (0.59) | KEAP1CA12CA9NR3C1FABP3 | |
| SCHEMBL17611095 | 0.77 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL3830399 | 0.76 | F10 (0.51) | NR3C1ALDH1A1SMN1; SMN2HTTF10 | |
| SCHEMBL13964840 | 0.76 | F10 (0.51) | NR3C1ALDH1A1SMN1; SMN2HTTF10 | |
| SCHEMBL21923051 | 0.76 | FABP4 (0.49) | NR3C1FABP3FABP4FABP5ALDH1A1 | |
| SCHEMBL23045698 | 0.76 | NR3C1 (0.51) | NR3C1FABP3FABP4FABP5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |