SCHEMBL2305282

SCHEMBL2305282

CCCCCCCCCCCC(=O)CC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PYGB P11216 2/20 0.47
MAPK1 P28482 1/20 0.44
GAA P10253 1/20 0.42
PRKCA P17252 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
GJB2 P29033 1/20 0.40
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PTPN1 P18031 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3878575 1.00 PYGB (0.47) PYGBMAPK1GAAPRKCAMAPT
SCHEMBL12198733 0.98 PYGB (0.48) PYGBMAPK1GAAPRKCAGJB2
SCHEMBL2507136 0.98 PYGB (0.48) PYGBMAPK1GAAPRKCAGJB2
SCHEMBL2302510 0.98 PYGB (0.48) PYGBMAPK1GAAPRKCAGJB2
SCHEMBL12198736 0.86 LGALS8 (0.53) MAPK1GJB2KDM4EPOLBSMN1; SMN2
SCHEMBL10301424 0.86 LGALS8 (0.53) MAPK1GJB2KDM4EPOLBSMN1; SMN2
SCHEMBL2794643 0.81 SELP (0.45) PYGBGAA
SCHEMBL2792078 0.81 SELP (0.45) PYGBGAA
SCHEMBL27806724 0.81 SELP (0.45) PYGBGAA
SCHEMBL12088003 0.80 CETP (0.45) MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2350108-B1 C-GLYCOSIDE COMPOUNDS, AND METHOD FOR PREPARING C-GLYCOSIDE COMPOUNDS ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) 2014-04-30 EP disclosed
US-8569467-B2 C-glycoside compounds, and method for preparing C-glycoside compounds ECOLE NATIONALE SUPÉRIEURE DE CHIMIE DE RENNES (FR) 2013-10-29 US disclosed
US-20110245490-A1 C-GLYCOSIDE COMPOUNDS, AND METHOD FOR PREPARING C-GLYCOSIDE COMPOUNDS ARMOR PROTEINES (FR) 2011-10-06 US disclosed
EP-2350108-A2 C-GLYCOSIDE COMPOUNDS, AND METHOD FOR PREPARING C-GLYCOSIDE COMPOUNDS Ecole Nationale Superieure de Chimie de Rennes (FR) 2011-08-03 EP disclosed
WO-2010052314-A2 C-GLYCOSIDE COMPOUNDS, AND METHOD FOR PREPARING C-GLYCOSIDE COMPOUNDS ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) 2010-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245490-A1 C-GLYCOSIDE COMPOUNDS, AND METHOD FOR PREPARING C-GLYCOSIDE COMPOUNDS FUT5, FUT6, CSGALNACT1 PYGB 750/4885MAPK1 751/4885GAA 778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.