SCHEMBL12198736

SCHEMBL12198736

CCCCCCCCCCCC(=O)C[C@@H]1OC(CO)[C@@H](O[C@@H]2OC(CO)[C@H](O)[C@H](O)C2O)[C@H](O)C1O

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 3/20 0.53
LGALS3 P17931 3/20 0.53
LGALS4 P56470 3/20 0.53
GJB2 P29033 2/20 0.51
KDM4E B2RXH2 1/20 0.51
POLB P06746 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
IGF2R P11717 1/20 0.43
MAPK1 P28482 1/20 0.43
TLR4 O00206 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10301424 1.00 LGALS8 (0.53) LGALS8LGALS3LGALS4GJB2KDM4E
SCHEMBL2305282 0.86 PYGB (0.47) GJB2KDM4EPOLBSMN1; SMN2MAPK1
SCHEMBL3878575 0.86 PYGB (0.47) GJB2KDM4EPOLBSMN1; SMN2MAPK1
SCHEMBL21391533 0.85 LGALS3 (0.47) LGALS8LGALS3LGALS4GJB2KDM4E
SCHEMBL12198733 0.85 PYGB (0.48) GJB2MAPK1
SCHEMBL2507136 0.85 PYGB (0.48) GJB2MAPK1
SCHEMBL2302510 0.85 PYGB (0.48) GJB2MAPK1
SCHEMBL9347500 0.85 GJB2 (0.52) LGALS8LGALS3LGALS4GJB2KDM4E
SCHEMBL11504400 0.85 GJB2 (0.52) LGALS8LGALS3LGALS4GJB2KDM4E
SCHEMBL22034095 0.85 GJB2 (0.52) LGALS8LGALS3LGALS4GJB2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8569467-B2 C-glycoside compounds, and method for preparing C-glycoside compounds ECOLE NATIONALE SUPÉRIEURE DE CHIMIE DE RENNES (FR) 2013-10-29 US disclosed
US-20110245490-A1 C-GLYCOSIDE COMPOUNDS, AND METHOD FOR PREPARING C-GLYCOSIDE COMPOUNDS ARMOR PROTEINES (FR) 2011-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245490-A1 C-GLYCOSIDE COMPOUNDS, AND METHOD FOR PREPARING C-GLYCOSIDE COMPOUNDS FUT5, FUT6, CSGALNACT1 LGALS8 469/4885LGALS3 101/4885LGALS4 217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.