Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27654241 | 0.75 | NOS1 (0.50) | NOS1NOS2TAAR1TSHRNOS3 | |
| SCHEMBL20286147 | 0.71 | PRKCZ (0.40) | NOS2NOS3PDE5AKDM1ASLC6A2 | |
| SCHEMBL16864596 | 0.70 | NOS1 (0.46) | NOS1NOS2TAAR1TSHRNOS3 | |
| SCHEMBL30642791 | 0.70 | NOS2 (0.46) | NOS1NOS2TAAR1TSHRNOS3 | |
| SCHEMBL23891653 | 0.70 | GSK3B (0.36) | NOS2NOS3KDM1ASLC6A2HTR2C | |
| SCHEMBL23891752 | 0.70 | PDE5A (0.32) | PDE5ARIPK1HTR2C | |
| SCHEMBL5889312 | 0.69 | NOS1 (0.49) | NOS1NOS2TAAR1NOS3MAPT | |
| SCHEMBL14457938 | 0.67 | KIF11 (0.43) | NOS1NOS2TAAR1TSHRNOS3 | |
| SCHEMBL23878327 | 0.66 | GSK3B (0.37) | NOS2NOS3KDM1A | |
| SCHEMBL22039450 | 0.66 | GSK3B (0.37) | NOS2NOS3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039997-A1 | CHEMICALLY COMPATIBILIZED FLUOROPOLYMER BLENDS | DAIKIN AMERICA, INC. (US) | 2021-03-04 | — | — | WO | disclosed |