Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23891653 | 0.77 | GSK3B (0.36) | PRKCZPRCPHTR2AHTR2CHTR2B | |
| SCHEMBL22039450 | 0.72 | GSK3B (0.37) | PRCP | |
| SCHEMBL23878327 | 0.72 | GSK3B (0.37) | PRCP | |
| SCHEMBL23054751 | 0.70 | NOS1 (0.46) | PDE5AHTR2CRIPK1 | |
| SCHEMBL38651941 | 0.70 | MAOB (0.39) | — | |
| SCHEMBL14540777 | 0.67 | NOS3 (0.40) | — | |
| SCHEMBL6310815 | 0.65 | ACHE (0.40) | CYP19A1HTR2AHTR2CHTR2BTHRB | |
| SCHEMBL13944940 | 0.64 | NOS3 (0.37) | — | |
| SCHEMBL13906325 | 0.62 | SLC18A3 (0.40) | HTR2C | |
| SCHEMBL13906324 | 0.62 | SLC18A3 (0.40) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |