Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852400 | 0.89 | HCAR2 (0.38) | HCAR2THRBAKR1B10AKR1B1ALOX5 | |
| SCHEMBL8899643 | 0.88 | HCAR2 (0.39) | HCAR2THRBAKR1B10AKR1B1ALOX5 | |
| SCHEMBL230779 | 0.88 | HCAR2 (0.39) | HCAR2THRBAKR1B10AKR1B1ALOX5 | |
| SCHEMBL230344 | 0.85 | THRB (0.56) | HCAR2THRBAKR1B10AKR1B1L3MBTL1 | |
| SCHEMBL2166950 | 0.84 | ATM (0.37) | HCAR2THRBAKR1B10AKR1B1ALOX5 | |
| SCHEMBL1537191 | 0.82 | HCAR2 (0.44) | HCAR2AKR1B10AKR1B1ALOX5L3MBTL1 | |
| SCHEMBL4623580 | 0.81 | HCAR2 (0.40) | HCAR2AKR1B10AKR1B1ALOX5ATM | |
| SCHEMBL22092326 | 0.81 | HCAR2 (0.40) | HCAR2AKR1B10AKR1B1ALOX5ATM | |
| SCHEMBL7794491 | 0.80 | HCAR2 (0.39) | HCAR2AKR1B10AKR1B1ALOX5ATM | |
| SCHEMBL10629493 | 0.79 | HCAR2 (0.41) | HCAR2AKR1B10AKR1B1ALOX5ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7750087-B2 | Modified polymers prepared with lanthanide-based catalysts | BRIDGESTONE CORPORATION (JP) | 2010-07-06 | — | — | US | claimed |
| EP-1298166-B1 | RUBBER COMPOSITION | JSR CORP (JP) | 2007-02-21 | — | — | EP | claimed |
| US-20060030677-A1 | Prepared by polymerizing conjugated monomer with a lanthanide-based catalyst to form a pseudo-living polymer and reacting the polymer with a di- or trihydrocarbyloxysilane having a reactive functional group such as (meth)acrylate, epoxy, or isocyanate that forms a chemical bond with the polymer; curable | ENEOS MATERIALS CORPORATION (JP) | 2006-02-09 | — | — | US | claimed |
| US-6992147-B1 | Modified polymers prepared with lanthanide-based catalysts | BRIDGESTONE CORPORATION (JP) | 2006-01-31 | — | — | US | claimed |
| US-6699935-B2 | A CROSSLINKED RUBBER PARTICLES CONTAINING CONJUGATED DIENE MONOMER, AROMATIC VINYL MONOMER AND MONOMER WITH AT LEAST TWO POLYMERIZABLE UNSATURATED GROUPS DISPERSED IN A CONJUGATED DIENE/AROMATIC VINYL COPOLYMER; RESIST TO ROLLING, SKID, WEAR | JSR CORPORATION (JP) | 2004-03-02 | — | — | US | claimed |
| US-6653404-B2 | Melt processability; dimensional stability | JSR CORPORATION (JP) | 2003-11-25 | — | — | US | claimed |
| EP-1298166-A1 | RUBBER COMPOSITION | JSR Corporation (JP) | 2003-04-02 | — | — | EP | claimed |
| US-20010053813-A1 | Rubber compositions | JSR CORPORATION (JP) | 2001-12-20 | — | — | US | claimed |
| EP-4349902-A1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2024-04-10 | — | — | EP | disclosed |
| EP-3851489-A1 | MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT | BRIDGESTONE CORPORATION (JP) | 2021-07-21 | — | — | EP | disclosed |
| EP-3730547-A1 | RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2020-10-28 | — | — | EP | disclosed |
| EP-3725836-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2020-10-21 | — | — | EP | disclosed |
| US-20180244808-A1 | METHOD FOR PRODUCING MODIFIED DIENE-BASED RUBBER, RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2018-08-30 | — | — | US | disclosed |
| EP-3345933-A1 | METHOD FOR PRODUCING MODIFIED DIENE RUBBER, RUBBER COMPOSITION, AND TIRE | Bridgestone Corporation (JP) | 2018-07-11 | — | — | EP | disclosed |
| US-20020007011-A1 | Crosslinked rubber particles and rubber compositions | JSR CORPORATION (JP) | 2002-01-17 | — | — | US | disclosed |
| US-20010053813-A1 | Rubber compositions | JSR CORPORATION (JP) | 2001-12-20 | — | — | US | disclosed |
| EP-1152030-A2 | Rubber mixtures based on crosslinked rubber particles and non-crosslinked rubbers | JSR Corporation (JP) | 2001-11-07 | — | — | EP | disclosed |
| EP-1149866-A2 | Rubber mixtures based on crosslinked rubber particles and non-crosslinked rubbers | JSR Corporation (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-1149867-A2 | Crosslinked rubber particles and rubber compositions | JSR Corporation (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5700874-A | CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE | BRIDGESTONE CORPORATION (JP) | 1997-12-23 | — | — | US | disclosed |