SCHEMBL230779

SCHEMBL230779

CC=CC(=O)OCCC[Si](Oc1ccccc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.39
THRB P10828 2/20 0.39
AKR1B10 O60218 4/20 0.39
AKR1B1 P15121 4/20 0.39
ALOX5 P09917 2/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
EGFR P00533 1/20 0.35
BTK Q06187 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8899643 0.89 HCAR2 (0.39) HCAR2THRBAKR1B10AKR1B1ALOX5
SCHEMBL852400 0.88 HCAR2 (0.38) HCAR2THRBAKR1B10AKR1B1ALOX5
SCHEMBL230551 0.88 HCAR2 (0.38) HCAR2THRBAKR1B10AKR1B1ALOX5
SCHEMBL2166950 0.85 ATM (0.37) HCAR2THRBAKR1B10AKR1B1ALOX5
SCHEMBL231329 0.83 THRB (0.59) HCAR2THRBAKR1B10AKR1B1L3MBTL1
SCHEMBL5898832 0.81 HCAR2 (0.38) HCAR2AKR1B10AKR1B1ALOX5ATM
SCHEMBL393259 0.80 HCAR2 (0.37) HCAR2AKR1B10AKR1B1ALOX5ATM
SCHEMBL17287255 0.80 HCAR2 (0.41) HCAR2AKR1B10AKR1B1ALOX5ATM
SCHEMBL10629493 0.80 HCAR2 (0.41) HCAR2AKR1B10AKR1B1ALOX5ATM
SCHEMBL17373023 0.80 HCAR2 (0.41) HCAR2AKR1B10AKR1B1ALOX5ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060030677-A1 Prepared by polymerizing conjugated monomer with a lanthanide-based catalyst to form a pseudo-living polymer and reacting the polymer with a di- or trihydrocarbyloxysilane having a reactive functional group such as (meth)acrylate, epoxy, or isocyanate that forms a chemical bond with the polymer; curable ENEOS MATERIALS CORPORATION (JP) 2006-02-09 US claimed
US-6992147-B1 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2006-01-31 US claimed
US-9593234-B2 Rubber composition having intramolecular double bond THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-03-14 US disclosed
EP-1950239-B1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO LTD (JP) 2017-01-04 EP disclosed
US-20150329708-A1 RUBBER COMPOSITION HAVING INTRAMOLECULAR DOUBLE BOND THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-11-19 US disclosed
US-8934165-B2 Electrophoretic particle, manufacturing method of electrophoretic particle, electrophoretic dispersed liquid, electrophoretic sheet, electrophoretic apparatus, and electronic equipment SEIKO EPSON CORPORATION (JP) 2015-01-13 US disclosed
US-20140206801-A1 INORGANIC OXIDE TRANSPARENT DISPERSION, RESIN COMPOSITION USED TO FORM TRANSPARENT COMPOSITE, TRANSPARENT COMPOSITE, AND OPTICAL MEMBER SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2014-07-24 US disclosed
EP-2752392-A1 INORGANIC OXIDE TRANSPARENT DISPERSION AND RESIN COMPOSITION FOR FORMING TRANSPARENT COMPOSITE, AND TRANSPARENT COMPOSITE AND OPTICAL MEMBER Sumitomo Osaka Cement Co., Ltd. (JP) 2014-07-09 EP disclosed
US-8679578-B2 Method of manufacturing anti-reflection film, anti-reflection film and coating composition FUJIFILM CORPORATION (JP) 2014-03-25 US disclosed
US-8557926-B2 Method for producing modified polymer THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-10-15 US disclosed
US-20130265632-A1 ELECTROPHORETIC PARTICLE, MANUFACTURING METHOD OF ELECTROPHORETIC PARTICLE, ELECTROPHORETIC DISPERSED LIQUID, ELECTROPHORETIC SHEET, ELECTROPHORETIC APPARATUS, AND ELECTRONIC EQUIPMENT SEIKO EPSON CORPORATION (JP) 2013-10-10 US disclosed
US-20060030677-A1 Prepared by polymerizing conjugated monomer with a lanthanide-based catalyst to form a pseudo-living polymer and reacting the polymer with a di- or trihydrocarbyloxysilane having a reactive functional group such as (meth)acrylate, epoxy, or isocyanate that forms a chemical bond with the polymer; curable ENEOS MATERIALS CORPORATION (JP) 2006-02-09 US disclosed
US-6992147-B1 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2006-01-31 US disclosed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
EP-1469002-A1 Method for stabilizing unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2004-10-20 EP disclosed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed
EP-1249454-A1 Preparation of unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2002-10-16 EP disclosed
US-5700874-A CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE BRIDGESTONE CORPORATION (JP) 1997-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 HCAR2 1784/4885THRB 4533/4885AKR1B10 82/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.