Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230551 | 0.89 | HCAR2 (0.38) | HCAR2THRBAKR1B10AKR1B1ALOX5 | |
| SCHEMBL230779 | 0.88 | HCAR2 (0.39) | HCAR2THRBAKR1B10AKR1B1ALOX5 | |
| SCHEMBL8899643 | 0.88 | HCAR2 (0.39) | HCAR2THRBAKR1B10AKR1B1ALOX5 | |
| SCHEMBL230731 | 0.85 | THRB (0.56) | THRBAKR1B10AKR1B1L3MBTL1ZDHHC2 | |
| SCHEMBL2166950 | 0.84 | ATM (0.37) | HCAR2THRBAKR1B10AKR1B1ALOX5 | |
| SCHEMBL9764056 | 0.83 | HCAR2 (0.38) | HCAR2AKR1B10AKR1B1ALOX5ATM | |
| SCHEMBL1398281 | 0.82 | HCAR2 (0.37) | HCAR2AKR1B10AKR1B1ALOX5ATM | |
| SCHEMBL1537284 | 0.82 | HCAR2 (0.44) | HCAR2AKR1B10AKR1B1ALOX5L3MBTL1 | |
| SCHEMBL22092326 | 0.81 | HCAR2 (0.40) | HCAR2AKR1B10AKR1B1ALOX5ATM | |
| SCHEMBL4623580 | 0.81 | HCAR2 (0.40) | HCAR2AKR1B10AKR1B1ALOX5ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289992-B1 | RUBBER COMPOSITION AND TIRE USING THE SAME | BRIDGESTONE CORP (JP) | 2012-12-19 | — | — | EP | disclosed |
| US-8247590-B2 | Method for preventing polymerization of unsaturated organosilicon compounds | WACKER CHEMIE AG (DE) | 2012-08-21 | — | — | US | disclosed |
| EP-2334690-B1 | METHOD FOR PRODUCING (METH)ACRYLOSILANES | WACKER CHEMIE AG (DE) | 2012-07-25 | — | — | EP | disclosed |
| US-8222337-B2 | Rubber composition and tire using the same | BRIDGESTONE CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| EP-2300486-B1 | METHOD FOR PREVENTING POLYMERIZATION OF UNSATURATED ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| US-20110118493-A1 | METHOD FOR PREVENTING POLYMERIZATION OF UNSATURATED ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20110092633-A1 | RUBBER COMPOSITION AND TIRE USING THE SAME | BRIDGESTONE CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| EP-2289992-A1 | RUBBER COMPOSITION AND TIRE USING THE SAME | Bridgestone Corporation (JP) | 2011-03-02 | — | — | EP | disclosed |
| US-7619108-B2 | Process for preparing unsaturated organosilicon compounds | WACKER CHEMIE AG (DE) | 2009-11-17 | — | — | US | disclosed |
| US-20080293958-A1 | Process for Preparing Unsaturated Organosilicon Compounds | WACKER CHEMIE AG (DE) | 2008-11-27 | — | — | US | disclosed |
| EP-1323775-B1 | DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND METHOD FOR PRODUCING THE SAME AND RUBBER COMPOSITION | JSR CORP (JP) | 2008-04-30 | — | — | EP | disclosed |
| US-6841694-B2 | Process for stabilizing unsaturated organosilicon compounds | WACKER-CHEMIE GMBH (DE) | 2005-01-11 | — | — | US | disclosed |
| US-6815554-B2 | REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS | WACKER-CHEMIE GMBH (DE) | 2004-11-09 | — | — | US | disclosed |
| EP-1469002-A1 | Method for stabilizing unsaturated organo-silicon compounds | Wacker-Chemie GmbH (DE) | 2004-10-20 | — | — | EP | disclosed |
| US-20040171859-A1 | Process for stabilizing unsaturated organosilicon compounds | WACKER-CHEMIE GMBH (DE) | 2004-09-02 | — | — | US | disclosed |
| US-20040030027-A1 | Diene rubber/inorganic compound composite and method for producing the same and rubber composition | BRIDGESTONE CORPORATION (JP) | 2004-02-12 | — | — | US | disclosed |
| US-20020151736-A1 | PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS | WACKER-CHEMIE GMBH (DE) | 2002-10-17 | — | — | US | disclosed |
| EP-1249454-A1 | Preparation of unsaturated organo-silicon compounds | Wacker-Chemie GmbH (DE) | 2002-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171859-A1 | Process for stabilizing unsaturated organosilicon compounds | ELOVL1, ELOVL6, DEGS1 | HCAR2 1784/4885THRB 4533/4885AKR1B10 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.