Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | RRM2 | P31350 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29162116 | 0.98 | SLC22A12 (0.38) | SLC22A12CYP2C9SLC22A6SLC22A8SLC22A11 | |
| SCHEMBL8171100 | 0.86 | TRPV4 (0.52) | SLC22A12CYP2C9SLC22A6SLC22A8SLC22A11 | |
| Hydrochloric Acid SCHEMBL29162081 | 0.84 | TRPV4 (0.50) | SLC22A12CYP2C9SLC22A6SLC22A8SLC22A11 | |
| SCHEMBL14283237 | 0.83 | CA12 (0.38) | SLC22A12CYP2C9SLC22A6SLC22A8SLC22A11 | |
| SCHEMBL25894839 | 0.82 | KIF11 (0.37) | SLC22A12CYP2C9SLC22A6SLC22A8SLC22A11 | |
| SCHEMBL21016949 | 0.80 | TGFBR1 (0.40) | SLC22A12CYP2C9SLC22A6SLC22A8SLC22A11 | |
| SCHEMBL22601556 | 0.80 | CA12 (0.35) | SLC22A12CYP2C9SLC22A6SLC22A8SLC22A11 | |
| SCHEMBL18536507 | 0.77 | MAPT (0.35) | SLC22A12CYP2C9SLC22A6SLC22A8SLC22A11 | |
| SCHEMBL22001498 | 0.76 | CHRNA7 (0.43) | CYP2C9CA12CA1CA2RRM2 | |
| SCHEMBL30074800 | 0.73 | TRPV4 (0.47) | SLC22A12CYP2C9SLC22A6SLC22A8SLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234951-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2023-07-27 | — | — | US | disclosed |
| WO-2021039961-A1 | RING-FUSED PYRAZOLE DERIVATIVE | 大日本住友製薬株式会社 | 2021-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234951-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | CYCS, CYP2E1, AHR | SLC22A12 3805/4885CYP2C9 24/4885SLC22A6 3403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.