Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | LGMN | Q99538 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23055347 | 0.90 | L3MBTL1 (0.43) | L3MBTL1TSHRHTTMAPK1ALDH1A1 | |
| SCHEMBL23055533 | 0.88 | L3MBTL1 (0.46) | L3MBTL1TSHRHTTMAPK1ALDH1A1 | |
| SCHEMBL23055460 | 0.86 | L3MBTL1 (0.45) | L3MBTL1TSHRHTTMAPK1ALDH1A1 | |
| SCHEMBL23055466 | 0.86 | L3MBTL1 (0.43) | L3MBTL1TSHRHTTMAPK1ALDH1A1 | |
| SCHEMBL23055842 | 0.85 | L3MBTL1 (0.43) | L3MBTL1TSHRHTTMAPK1ALDH1A1 | |
| SCHEMBL23055875 | 0.84 | MAPT (0.38) | L3MBTL1MAPK1ALDH1A1KMT2AGAA | |
| SCHEMBL23055447 | 0.84 | MAPT (0.37) | L3MBTL1MAPK1ALDH1A1KMT2AGAA | |
| SCHEMBL23055851 | 0.80 | KIF11 (0.40) | L3MBTL1MAPK1ALDH1A1LMNAGAA | |
| SCHEMBL23055488 | 0.79 | KIF11 (0.38) | L3MBTL1HTTALDH1A1LMNAKMT2A | |
| SCHEMBL23055871 | 0.74 | MAPT (0.36) | L3MBTL1MAPK1ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795147-B2 | Modulators of complex I | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| US-11795147-B2 | Modulators of complex I | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| US-20210061761-A1 | MODULATORS OF COMPLEX I | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210061761-A1 | MODULATORS OF COMPLEX I | NDUFAB1, NDUFV1, NDUFB7 | L3MBTL1 4159/4885TSHR 4099/4885HTT 2574/4885 |
| US-11795147-B2 | Modulators of complex I | NDUFAB1, NDUFV1, NDUFB7 | L3MBTL1 4159/4885TSHR 4099/4885HTT 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.