Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23060180 | 0.91 | GSTO1 (0.41) | GSTO1JAK3LMNAALDH1A1JAK2 | |
| SCHEMBL21431003 | 0.85 | GSTO1 (0.46) | GSTO1JAK3LMNAALDH1A1JAK2 | |
| SCHEMBL23060271 | 0.82 | KDM4E (0.38) | LMNAALDH1A1SMN1; SMN2KMT2ATGM2 | |
| SCHEMBL28553497 | 0.78 | KDM4E (0.42) | LMNAALDH1A1SMN1; SMN2KMT2ATGM2 | |
| SCHEMBL23060172 | 0.78 | TGM2 (0.34) | LMNAALDH1A1SMN1; SMN2TGM2CA12 | |
| SCHEMBL23060201 | 0.77 | GSTO1 (0.47) | GSTO1JAK3LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL23044920 | 0.77 | GSTO1 (0.44) | GSTO1JAK3LMNAALDH1A1JAK2 | |
| SCHEMBL23044908 | 0.75 | GSTO1 (0.43) | GSTO1JAK3LMNAALDH1A1JAK2 | |
| SCHEMBL21430983 | 0.73 | ALDH1A1 (0.50) | GSTO1JAK3LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL23060058 | 0.71 | EGFR (0.40) | GSTO1JAK3LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021037219-A1 | PYRAZOLE DERIVATIVE FOR FGFR INHIBITOR AND PREPARATION METHOD THEREFOR | 上海奕拓医药科技有限责任公司 | 2021-03-04 | — | — | WO | disclosed |