Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23271256 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL23062809 | 0.90 | BCAT2 (0.43) | SMN1; SMN2ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL23271259 | 0.90 | RAB9A (0.41) | SMN1; SMN2ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL23062752 | 0.88 | ACKR3 (0.42) | SMN1; SMN2ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL23271260 | 0.88 | KDM4E (0.39) | SMN1; SMN2ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL23310020 | 0.86 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL23062720 | 0.86 | KDM4E (0.39) | SMN1; SMN2ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL23062777 | 0.86 | UNG (0.41) | SMN1; SMN2ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL23271258 | 0.85 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL23271261 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1RAB9AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250049804-A1 | FERROCHELATASE INHIBITORS AND METHODS OF USE | UNIV INDIANA RES & TECH CORP (US) | 2025-02-13 | — | — | US | disclosed |
| US-12161642-B2 | Ferrochelatase inhibitors and methods of use | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2024-12-10 | — | — | US | disclosed |
| US-20210121465-A1 | FERROCHELATASE INHIBITORS AND METHODS OF USE | GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2021-04-29 | — | — | US | disclosed |
| US-20210121465-A1 | FERROCHELATASE INHIBITORS AND METHODS OF USE | GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2021-04-29 | — | — | US | disclosed |
| EP-3787630-A1 | FERROCHELATASE INHIBITORS AND METHODS OF USE | Indiana University Research and Technology Corporation (US) | 2021-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250049804-A1 | FERROCHELATASE INHIBITORS AND METHODS OF USE | FECH, SLC40A1, TPI1 | SMN1; SMN2 2465/4885ALDH1A1 701/4885RAB9A 2556/4885 |
| US-20210121465-A1 | FERROCHELATASE INHIBITORS AND METHODS OF USE | FECH, SLC40A1, TPI1 | SMN1; SMN2 2465/4885ALDH1A1 701/4885RAB9A 2556/4885 |
| US-12161642-B2 | Ferrochelatase inhibitors and methods of use | FECH, SLC40A1, TPI1 | SMN1; SMN2 2465/4885ALDH1A1 701/4885RAB9A 2556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.