Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23063518 | 0.89 | MMP9 (0.41) | TAS2R14PDE1BMMP1MMP9MMP13 | |
| SCHEMBL23063244 | 0.84 | MAPT (0.46) | NPBWR1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6637022 | 0.68 | KDM4E (0.45) | NPBWR1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6581311 | 0.67 | NR1H3 (0.65) | ADORA2AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6580895 | 0.67 | NR1H3 (0.59) | ADORA2A | |
| SCHEMBL15556088 | 0.67 | MAPT (0.40) | NPBWR1ADORA2AMAPTKMT2AKDM4E | |
| SCHEMBL24569975 | 0.66 | TSPO (0.42) | NPBWR1KMT2AMEN1 | |
| SCHEMBL17397875 | 0.66 | HTR6 (0.40) | KMT2AMEN1 | |
| SCHEMBL16014513 | 0.66 | MAPT (0.50) | PDE1BNPBWR1MAPTKMT2AKDM4E | |
| SCHEMBL23508463 | 0.66 | KDM4E (0.43) | MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3788041-A1 | NOVEL COMPOUNDS | Inflazome Limited (IE) | 2021-03-10 | — | — | EP | disclosed |