Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23063153 | 0.89 | TAS2R14 (0.40) | MMP9MMP1MMP13ADAM17PDE1B | |
| SCHEMBL23063244 | 0.86 | MAPT (0.46) | NPBWR1SMN1; SMN2MAPTALDH1A1HTT | |
| SCHEMBL23063246 | 0.76 | NLRP3 (0.43) | MMP9MMP1MMP13ADAM17CHRM2 | |
| SCHEMBL15556088 | 0.73 | MAPT (0.40) | CHRM2APLNRNPBWR1SMN1; SMN2MAPT | |
| SCHEMBL16014513 | 0.72 | MAPT (0.50) | PDE1BNPBWR1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6637022 | 0.71 | KDM4E (0.45) | NPBWR1SMN1; SMN2MAPTALDH1A1HTT | |
| SCHEMBL24569975 | 0.70 | TSPO (0.42) | NPBWR1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL23508463 | 0.69 | KDM4E (0.43) | SMN1; SMN2MAPTPTGS2ALDH1A1HTT | |
| SCHEMBL24569765 | 0.69 | KDM4E (0.42) | NPBWR1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL24569178 | 0.69 | PDE8B (0.39) | NPBWR1SMN1; SMN2MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3788041-A1 | NOVEL COMPOUNDS | Inflazome Limited (IE) | 2021-03-10 | — | — | EP | disclosed |