Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23063518 | 0.86 | MMP9 (0.41) | MAPTNPBWR1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL23063153 | 0.84 | TAS2R14 (0.40) | MAPTKDM4EKMT2ANPBWR1MEN1 | |
| SCHEMBL23063346 | 0.77 | KDM4E (0.48) | MAPTKDM4EKMT2ALMNAHTT | |
| SCHEMBL6637022 | 0.75 | KDM4E (0.45) | MAPTKDM4ENPBWR1LMNAHTT | |
| SCHEMBL23508463 | 0.73 | KDM4E (0.43) | MAPTKDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL16014513 | 0.73 | MAPT (0.50) | MAPTKDM4EKMT2ANPBWR1ALDH1A1 | |
| SCHEMBL24569765 | 0.72 | KDM4E (0.42) | MAPTKDM4ENPBWR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15538235 | 0.72 | CMA1 (0.43) | MAPTKDM4ENPBWR1LMNAALDH1A1 | |
| SCHEMBL23063436 | 0.71 | DGAT1 (0.35) | MAPTKDM4EKMT2ALMNAALDH1A1 | |
| SCHEMBL24569972 | 0.71 | PDE8B (0.42) | MAPTNPBWR1ALDH1A1L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533913-A | Novel compounds | 英夫拉索姆有限公司 | 2021-03-19 | — | — | CN | disclosed |
| EP-3788041-A1 | NOVEL COMPOUNDS | Inflazome Limited (IE) | 2021-03-10 | — | — | EP | disclosed |