SCHEMBL2307166

SCHEMBL2307166

N=C(c1ccccc1)c1ccccc1N

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.57
GAA P10253 1/20 0.57
F2 P00734 1/20 0.46
F10 P00742 1/20 0.46
F12 P00748 1/20 0.46
F7 P08709 1/20 0.46
F3 P13726 1/20 0.46
PKM P14618 1/20 0.46
BLM P54132 1/20 0.44
CYP1A2 P05177 1/20 0.44
POLB P06746 1/20 0.44
KMT2A Q03164 2/20 0.43
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
C1S P09871 1/20 0.43
PRSS3 P35030 1/20 0.43
RECQL P46063 1/20 0.43
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 3/20 0.41
CFTR P13569 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15811026 0.88 WDR5 (0.53) MAPTGAAKMT2APRSS1PRSS2
SCHEMBL9692808 0.87 PLAU (0.46) MAPTGAAF2BLMCYP1A2
SCHEMBL636319 0.85 MAPT (0.47) MAPTGAAF2F10F12
SCHEMBL5215773 0.84 HSD11B1 (0.44) MAPTGAAF2POLBKMT2A
SCHEMBL17742208 0.83 PRSS1 (0.58) MAPTGAAPOLBKMT2APRSS1
SCHEMBL28794373 0.83 CYP1A2 (0.52) MAPTGAAF2F10F12
SCHEMBL15810939 0.81 PRSS1 (0.46) MAPTGAAPOLBKMT2APRSS1
SCHEMBL22454059 0.79 MAPT (0.50) MAPTGAAF2F10F12
SCHEMBL5356130 0.79 POLB (0.46) MAPTGAAPOLBKMT2AALDH1A1
SCHEMBL13844371 0.79 CA2 (0.39) MAPTGAAPOLBALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60038380-A None JP disclosed
EP-3428163-B1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2024-02-28 EP disclosed
WO-2021261857-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2021-12-30 WO disclosed
US-11174258-B2 Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2021-11-16 US disclosed
EP-3783007-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2021-02-24 EP disclosed
EP-3140367-B1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2020-07-29 EP disclosed
WO-2019177243-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREFOR 덕산네오룩스 주식회사 2019-09-19 WO disclosed
US-20190002469-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2019-01-03 US disclosed
EP-3185325-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-06-28 EP disclosed
WO-2017104994-A1 COMPOSITION FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2017-06-22 WO disclosed
WO-1996030393-A1 A METHOD FOR THE SYNTHESIS OF MIXTURES OF COMPOUNDS WARNER-LAMBERT COMPANY (US) 1996-10-03 WO disclosed
WO-1995025116-A1 METHOD AND APPARATUS FOR PERFORMING MULTIPLE SEQUENTIAL REACTIONS ON A MATRIX CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1995-09-21 WO disclosed
EP-0663856-A1 APPARATUS AND METHOD FOR MULTIPLE SIMULTANEOUS SYNTHESIS WARNER-LAMBERT COMPANY (US) 1995-07-26 EP disclosed
US-5324483-A Apparatus for multiple simultaneous synthesis WARNER-LAMBERT COMPANY (US) 1994-06-28 US disclosed
US-5317018-A Antiepileptic agents FIDIA RESEARCH FOUNDATION 1994-05-31 US disclosed
WO-1994008711-A1 APPARATUS AND METHOD FOR MULTIPLE SIMULTANEOUS SYNTHESIS WARNER-LAMBERT COMPANY (US) 1994-04-28 WO disclosed
WO-1993025554-A1 BENZODIAZEPINES AND COMPOSITIONS FOR TREATING ANXIETY AND PANIC DISORDERS, AND IDIOPATHIC AND PSYCHOMOTOR EPILEPSY HOFFMANN-LA ROCHE INC. (US) 1993-12-23 WO disclosed
EP-0573982-A1 Benzodiazepines and their compositions for treating anxiety and panic disorders, and idiopathic and psychomotor epilepsy F. HOFFMANN-LA ROCHE AG (CH) 1993-12-15 EP disclosed
JP-S6038380-A IMPROVED SYNTHESIS OF 1-PIPERIDINYL-1,4-BENZODIAZEPINE SHIONOGI & CO LTD 1985-02-27 JP disclosed
US-3966793-A ORTHO-AMINOARYL KETIMINES CLIN MIDY (FR) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11174258-B2 Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes KCNH2, KCNH3, KCNJ2 MAPT 2580/4885GAA 1647/4885F2 1154/4885
US-20190002469-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES KCNH2, KCNH3, KCNJ2 MAPT 2580/4885GAA 1647/4885F2 1154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.