Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.46 |
| ▸ | MASP2 | O00187 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307166 | 0.87 | MAPT (0.57) | F2PRSS1PRSS3MAPTGAA | |
| SCHEMBL15811026 | 0.84 | WDR5 (0.53) | PRSS1PRSS3MAPTGAAHSD17B10 | |
| SCHEMBL5215773 | 0.84 | HSD11B1 (0.44) | PLAUF2PRSS1MAPTGAA | |
| SCHEMBL13844371 | 0.80 | CA2 (0.39) | MAPTGAAALDH1A1CA1CA2 | |
| SCHEMBL10778018 | 0.78 | MASP2 (0.54) | PLAUMASP2THPOF2PRSS1 | |
| SCHEMBL28795375 | 0.77 | BCAT2 (0.47) | PLAUMASP2THPOF2PRSS1 | |
| SCHEMBL251656 | 0.77 | PLAU (0.65) | PLAUMASP2THPOF2PRSS1 | |
| SCHEMBL22454059 | 0.76 | MAPT (0.50) | F2PRSS1APEX1PRSS3MAPT | |
| SCHEMBL17253748 | 0.76 | MMP3 (0.42) | MAPTGAACA1CA2CA9 | |
| SCHEMBL3178977 | 0.75 | MAPT (0.77) | MAPTGAAHSD17B10ALDH1A1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444158-A4 | CONJUGATED POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | — | 1992-06-24 | — | — | EP | disclosed |
| EP-0444158-A1 | CONJUGATED POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE. | UNIV CALIFORNIA (US) | 1991-09-04 | — | — | EP | disclosed |
| WO-1990005749-A1 | CONJUGATED POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-05-31 | — | — | WO | disclosed |