Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | ADH5 | P11766 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30463031 | 0.81 | CYP3A4 (0.61) | CYP3A4CYP2A6ENPP2MKNK1MKNK2 | |
| SCHEMBL15770888 | 0.77 | ENPP2 (0.63) | CYP3A4CYP2A6ENPP2MKNK1MKNK2 | |
| SCHEMBL25159951 | 0.73 | ENPP2 (0.39) | CYP3A4CYP2A6ENPP2MKNK1MKNK2 | |
| SCHEMBL2693122 | 0.73 | CYP3A4 (0.61) | CYP3A4CYP2A6ENPP2MKNK1MKNK2 | |
| SCHEMBL1559218 | 0.73 | CYP3A4 (0.52) | CYP3A4CYP2A6ENPP2MKNK1MKNK2 | |
| SCHEMBL14908640 | 0.73 | LMNA (0.58) | CYP3A4CYP2A6ENPP2MKNK1MKNK2 | |
| SCHEMBL17819393 | 0.72 | CYP3A4 (0.47) | CYP3A4CYP2A6ENPP2MKNK1MKNK2 | |
| SCHEMBL29956144 | 0.71 | ENPP2 (0.39) | CYP3A4CYP2A6ENPP2MKNK1MKNK2 | |
| SCHEMBL31057726 | 0.71 | KDM4E (0.44) | LMNAMAPTNOTUMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30710779 | 0.70 | KDM4E (0.43) | LMNAMAPTNOTUMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210147393-A1 | DIFLUOROMETHYL-PHENYL TRIAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-05-20 | — | — | US | disclosed |
| US-10941137-B2 | Difluoromethyl-phenyl triazoles | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10941137-B2 | Difluoromethyl-phenyl triazoles | GABRA5, GABRB1, GABRA1 | CYP3A4 253/4885CYP2A6 478/4885ENPP2 3748/4885 |
| US-20210147393-A1 | DIFLUOROMETHYL-PHENYL TRIAZOLES | GABRA5, GABRB1, GABRA1 | CYP3A4 233/4885CYP2A6 474/4885ENPP2 3770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.