SCHEMBL230732

SCHEMBL230732

C=C(C)C(=O)OCC(C)O[SiH](C)C

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.66
ALDH1A1 P00352 2/20 0.40
THRB P10828 1/20 0.39
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17922839 0.82 TSHR (0.47) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL7638659 0.81 TSHR (0.59) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL14576606 0.80 TDP1 (0.39) TSHRALDH1A1TDP1
SCHEMBL4331907 0.80 TSHR (0.76) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL537361 0.80 TSHR (0.53) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL5698745 0.80 TSHR (0.75) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL24562 0.80 TSHR (1.00) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL1782287 0.80 TSHR (0.49) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL536923 0.79 TSHR (0.52) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL160208 0.79 TSHR (0.73) TSHRALDH1A1THRBPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1833865-B1 CROSS-LINKABLE, SILANE-MODIFIED COPOLYMERS WACKER CHEMIE AG (DE) 2010-03-17 EP claimed
US-20080145676-A1 free radical copolymerization of a vinyl ester or acrylate monomer with a post-crosslinkable ethylenically unsaturated silane such as methacryloyloxymethylmethoxydimethylsilane; aqueous dispersion or water-redispersible powders; high storage stability with rapid cure; adhesive, cements, binder, coating WACKER CHEMIE AG (DE) 2008-06-19 US claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
CN-109803826-B Laminate and method for producing same 信越化学工业株式会社 2021-05-11 CN disclosed
CN-108472685-B Method for producing laminate 信越化学工业株式会社 2021-02-02 CN disclosed
CN-111533854-A Silicon modified acrylic resin and application thereof 上海亿祺化工技术有限公司 2020-08-14 CN disclosed
EP-3045506-B1 ACTINIC ENERGY RADIATION-CURABLE ACRYLIC SILICONE RESIN COMPOSITION AND COATED ARTICLE SHINETSU CHEMICAL CO (JP) 2020-03-04 EP disclosed
US-20190291394-A1 LAMINATED BODY AND PRODUCTION METHOD THEREFOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-09-26 US disclosed
EP-3527366-A1 LAMINATED BODY AND PRODUCTION METHOD THEREFOR Shin-Etsu Chemical Co., Ltd. (JP) 2019-08-21 EP disclosed
US-10196409-B2 Organosilicon compound and curable composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-02-05 US disclosed
EP-3210988-B1 ORGANOSILICON COMPOUND AND CURABLE COMPOSITION SHINETSU CHEMICAL CO (JP) 2018-06-20 EP disclosed
EP-1713822-A2 HCV NS-3 SERINE PROTEASE INHIBITORS Medivir Aktiebolag (SE) 2006-10-25 EP disclosed
WO-2006072407-A1 REACTIVE SILICIC ACID SUSPENSIONS WACKER CHEMIE AG (DE) 2006-07-13 WO disclosed
WO-2006072411-A1 CROSS-LINKABLE, SILANE-MODIFIED COPOLYMERS WACKER CHEMIE AG (DE) 2006-07-13 WO disclosed
WO-2005073216-A2 HCV NS-3 SERINE PROTEASE INHIBITORS MEDIVIR AB (SE) 2005-08-11 WO disclosed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885ALDH1A1 402/4885THRB 4533/4885
US-10196409-B2 Organosilicon compound and curable composition MASTL, PIEZO1, MCM6 TSHR 3198/4885ALDH1A1 1875/4885THRB 2691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.