Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 15/20 | 0.61 |
| ▸ | ATF1 | P18846 | 13/20 | 0.61 |
| ▸ | XPO1 | O14980 | 4/20 | 0.60 |
| ▸ | JUN | P05412 | 3/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.59 |
| ▸ | RELA | Q04206 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489466 | 0.89 | NFKB1 (0.59) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL1821585 | 0.83 | NFKB1 (0.57) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL15290081 | 0.81 | NFKB1 (0.56) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL4745582 | 0.80 | CNR2 (0.69) | NFKB1ATF1XPO1LMNA | |
| SCHEMBL6977551 | 0.80 | NFKB1 (0.62) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL15273207 | 0.79 | NFKB1 (0.54) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL6288528 | 0.79 | ATF1 (0.68) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL3380681 | 0.79 | CNR2 (0.64) | NFKB1ATF1XPO1 | |
| SCHEMBL3379524 | 0.79 | CNR2 (0.64) | NFKB1ATF1XPO1 | |
| SCHEMBL8518174 | 0.79 | NFKB1 (0.62) | NFKB1ATF1XPO1JUNNFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3095780-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2016-11-23 | — | — | EP | disclosed |
| US-9271499-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-01 | — | — | US | disclosed |
| US-9266830-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-23 | — | — | US | disclosed |
| US-20150073139-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2015-03-12 | — | — | US | disclosed |
| US-20150011553-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2015-01-08 | — | — | US | disclosed |
| US-8785647-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-20130310408-A1 | Pesticidal Arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-21 | — | — | US | disclosed |
| US-8450483-B2 | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2013-05-28 | — | — | US | disclosed |
| EP-2349994-A1 | PESTICIDAL (HETERO) ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-08-03 | — | — | EP | disclosed |
| US-20100216792-A1 | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2010-08-26 | — | — | US | disclosed |
| WO-2010043315-A1 | PESTICIDAL (HETERO) ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011553-A1 | Pesticidal Arylpyrrolidines | DDT, AADAC, AHR | NFKB1 3198/4885ATF1 2644/4885XPO1 4013/4885 |
| US-20100216792-A1 | Pesticidal arylpyrrolidines | DDT, AADAC, AHR | NFKB1 3198/4885ATF1 2644/4885XPO1 4013/4885 |
| US-20150073139-A1 | Pesticidal Arylpyrrolidines | DDT, ACHE, QDPR | NFKB1 2969/4885ATF1 3410/4885XPO1 4420/4885 |
| US-20130310408-A1 | Pesticidal Arylpyrrolidines | DDT, ACHE, QDPR | NFKB1 2969/4885ATF1 3410/4885XPO1 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.