Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26862225 | 0.83 | — | — | |
| SCHEMBL19864857 | 0.83 | LIMK1 (0.33) | LMNANUDT1HTTMEN1KMT2A | |
| SCHEMBL2316376 | 0.77 | CHEK1 (0.42) | LMNANUDT1MEN1KMT2ACHEK1 | |
| SCHEMBL20777978 | 0.77 | ADORA2A (0.30) | — | |
| SCHEMBL21090760 | 0.75 | NUDT1 (0.35) | LMNANUDT1HTTCHEK1AURKA | |
| SCHEMBL27404961 | 0.74 | RAB9A (0.30) | — | |
| SCHEMBL24409449 | 0.73 | NUDT1 (0.32) | LMNANUDT1HTTCHEK1AURKA | |
| SCHEMBL27404798 | 0.72 | ADORA2B (0.34) | — | |
| SCHEMBL26152241 | 0.71 | ADORA2A (0.33) | LMNANUDT1CHEK1AURKA | |
| SCHEMBL21706829 | 0.69 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024119117-A1 | MODIFIED 5' CAP FOR MRNA AND METHODS OF USE THEREOF | PRIME MEDICINE, INC. (US) | 2024-06-06 | — | — | WO | disclosed |
| WO-2021046426-A9 | CYCLIC DINUCLEOTIDE STING AGONISTS TETHERED TO A PD-1 OR CTLA-4 ANTIBODIES | SPEROVIE BIOSCIENCES, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
| WO-2021046426-A1 | CYCLIC DINUCLEOTIDE STING AGONISTS TETHERED TO A PD-1 OR CTLA-4 ANTIBODIES | SPEROVIE BIOSCIENCES, INC. (US) | 2021-03-11 | — | — | WO | disclosed |