Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23079428 | 0.83 | LMNA (0.33) | LMNANUDT1HTTMEN1KMT2A | |
| SCHEMBL26862225 | 0.78 | — | — | |
| SCHEMBL23906371 | 0.78 | — | — | |
| SCHEMBL22651230 | 0.77 | ADORA2A (0.33) | LIMK1L3MBTL1LMNACDC7DBF4 | |
| SCHEMBL19969968 | 0.74 | LIMK1 (0.33) | LIMK1L3MBTL1LMNANOS3NOS2 | |
| SCHEMBL22676747 | 0.72 | LIMK1 (0.34) | LIMK1L3MBTL1LMNANOS3NOS2 | |
| SCHEMBL17623163 | 0.70 | LIMK1 (0.38) | LIMK1L3MBTL1NOS3NOS2CDC7 | |
| SCHEMBL7519562 | 0.70 | — | — | |
| SCHEMBL21911228 | 0.67 | NUDT1 (0.34) | LMNANUDT1HTT | |
| SCHEMBL27404961 | 0.66 | RAB9A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765474-B1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER (US) | 2022-06-15 | — | — | EP | disclosed |
| WO-2018031818-A2 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2018-02-15 | — | — | WO | disclosed |