Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | NAE1 | Q13564 | 5/20 | 0.52 |
| ▸ | UBA3 | Q8TBC4 | 5/20 | 0.52 |
| ▸ | ATG7 | O95352 | 1/20 | 0.49 |
| ▸ | AHCY | P23526 | 3/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1795319 | 1.00 | CA2 (0.55) | CA2NAE1UBA3ATG7AHCY | |
| SCHEMBL17889860 | 0.91 | CA2 (0.46) | CA2NAE1UBA3ATG7AHCY | |
| SCHEMBL1797374 | 0.87 | AHCY (0.54) | CA2AHCYADORA2BRNASEL | |
| SCHEMBL23080212 | 0.87 | AHCY (0.54) | CA2AHCYADORA2BRNASEL | |
| SCHEMBL12617957 | 0.87 | CA2 (0.49) | CA2NAE1UBA3ATG7AHCY | |
| SCHEMBL12566881 | 0.86 | CA2 (0.53) | CA2NAE1UBA3AHCYADORA2B | |
| SCHEMBL17889858 | 0.84 | AHCY (0.42) | CA2NAE1UBA3ATG7AHCY | |
| SCHEMBL17898107 | 0.84 | ADORA3 (0.60) | CA2NAE1UBA3 | |
| SCHEMBL1796471 | 0.82 | NAE1 (0.47) | CA2NAE1UBA3ATG7 | |
| SCHEMBL23080270 | 0.82 | AHCY (0.51) | CA2AHCYADORA2BRNASEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210070798-A1 | Inhibitors of E1 activating enzymes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070798-A1 | Inhibitors of E1 activating enzymes | ECE1, RNASE1, RCE1 | CA2 3826/4885NAE1 41/4885UBA3 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.