Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525753 | 1.00 | GPR119 (0.43) | GPR119CTSSCTSKRIPK1LMNA | |
| SCHEMBL6232571 | 0.89 | RIPK1 (0.50) | GPR119CTSSCTSKRIPK1LMNA | |
| SCHEMBL26915519 | 0.86 | GAA (0.41) | GPR119CTSSCTSKRIPK1LMNA | |
| SCHEMBL25416693 | 0.78 | APLNR (0.41) | CTSSCTSKLMNAPOLBNQO2 | |
| SCHEMBL14564600 | 0.78 | TSHR (0.44) | LMNAPOLBNQO2GAAMEN1 | |
| SCHEMBL7328664 | 0.78 | HPGD (0.45) | LMNAPOLBGAAMEN1NPC1 | |
| SCHEMBL30525728 | 0.78 | GPR119 (0.43) | GPR119CTSSCTSKRIPK1SCN9A | |
| SCHEMBL23081322 | 0.78 | GPR119 (0.43) | GPR119CTSSCTSKRIPK1SCN9A | |
| SCHEMBL3180198 | 0.78 | ATM (0.53) | CTSSCTSKNQO2GAAMEN1 | |
| SCHEMBL23151027 | 0.77 | P2RX7 (0.43) | RIPK1LMNAP2RX7MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046515-A1 | INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-03-11 | — | — | WO | disclosed |