Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525753 | 0.86 | GPR119 (0.43) | GAACTSSCTSKLMNAPOLB | |
| SCHEMBL23081592 | 0.86 | GPR119 (0.43) | GAACTSSCTSKLMNAPOLB | |
| SCHEMBL6232571 | 0.86 | RIPK1 (0.50) | GAACTSSCTSKLMNAPOLB | |
| SCHEMBL7391934 | 0.81 | NPC1 (0.49) | GAALMNAPOLBMEN1NPC1 | |
| SCHEMBL25416693 | 0.76 | APLNR (0.41) | GAACTSSCTSKLMNAPOLB | |
| SCHEMBL7328664 | 0.76 | HPGD (0.45) | GAALMNAPOLBMEN1NPC1 | |
| SCHEMBL14564600 | 0.76 | TSHR (0.44) | GAALMNAPOLBNQO2MEN1 | |
| SCHEMBL23081322 | 0.76 | GPR119 (0.43) | GAACTSSCTSKANO1RIPK1 | |
| SCHEMBL30525728 | 0.76 | GPR119 (0.43) | GAACTSSCTSKANO1RIPK1 | |
| SCHEMBL3180198 | 0.76 | ATM (0.53) | GAACTSSCTSKNQO2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132475-A1 | SUBSTITUTED PYRAZOLYL COMPOUNDS AS MALT-1 INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2024-04-25 | — | — | US | disclosed |
| EP-4288417-A1 | SUBSTITUTED PYRAZOLYL COMPOUNDS AS MALT-1 INHIBITORS | Aurigene Oncology Limited (IN) | 2023-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132475-A1 | SUBSTITUTED PYRAZOLYL COMPOUNDS AS MALT-1 INHIBITORS | MALT1, FKBP1B, FKBP1A | GAA 69/4885CTSS 669/4885CTSK 739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.