Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 9/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4321426 | 0.76 | BACE1 (0.44) | BACE1BACE2PTGER4 | |
| SCHEMBL5614017 | 0.72 | MAOB (0.41) | BACE1MAOBMAOAPOLB | |
| SCHEMBL6569052 | 0.69 | BACE1 (0.46) | BACE1BACE2 | |
| SCHEMBL31668884 | 0.69 | BACE1 (0.60) | BACE1BACE2 | |
| SCHEMBL2168561 | 0.68 | CASP3 (0.41) | BACE1MAOBMAOABACE2PTGER4 | |
| SCHEMBL3363734 | 0.68 | BACE1 (0.35) | PTPN1BACE1POLBBACE2 | |
| SCHEMBL29575351 | 0.67 | GNPAT (0.52) | BACE1 | |
| SCHEMBL30483779 | 0.65 | NAALAD2 (0.64) | PTPN1BACE1POLBBACE2 | |
| SCHEMBL6930389 | 0.64 | MAOB (0.53) | MAOBMAOA | |
| SCHEMBL19750987 | 0.64 | BACE1 (0.56) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350121-A1 | ANTI-APOPTOTIC FUSION PROTEINS | Fändrich, Fred (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010052341-A1 | ANTI-APOPTOTIC FUSION PROTEINS | KUNZENDORF ULRICH (DE) | 2010-05-14 | — | — | WO | disclosed |