Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.52 |
| ▸ | NAE1 | Q13564 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22855845 | 0.88 | AGTR2 (0.54) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL23083143 | 0.86 | AGTR2 (0.53) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL4540588 | 0.86 | AGTR2 (0.55) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL23083038 | 0.85 | AGTR2 (0.61) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL4543320 | 0.85 | AGTR2 (0.53) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| Candesartan SCHEMBL19357208 | 0.84 | AGTR1 (0.73) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| Candesartan SCHEMBL3938 | 0.84 | AGTR1 (0.73) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| Candesartan SCHEMBL29508236 | 0.84 | AGTR1 (0.73) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| Candesartan SCHEMBL29682351 | 0.84 | AGTR1 (0.73) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL13302628 | 0.84 | AGTR2 (0.63) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220175667-A1 | Extracellular Matrices, Uses Thereof, and Methods of Making Extracellular Matrices | THE JOHNS HOPKINS UNIVERSITY | 2022-06-09 | — | — | US | disclosed |
| US-20210069375-A1 | Extracellular Matrices, Uses thereof, and Method for Making Extracellular Matrices | THE JOHNS HOPKINS UNIVERSITY | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210069375-A1 | Extracellular Matrices, Uses thereof, and Method for Making Extracellular Matrices | MMP1, MATR3, COL1A1 | AGTR2 4283/4885CYP3A4 2883/4885ADORA3 2833/4885 |
| US-20220175667-A1 | Extracellular Matrices, Uses Thereof, and Methods of Making Extracellular Matrices | EPCAM, CD44, MATR3 | AGTR2 4168/4885CYP3A4 2605/4885ADORA3 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.