Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23083349 | 0.79 | TAAR1 (0.54) | SMN1; SMN2RAB9ATAAR1ALDH1A1LMNA | |
| SCHEMBL27263888 | 0.78 | RAB9A (0.58) | SMN1; SMN2RAB9ANPC1TAAR1ALDH1A1 | |
| SCHEMBL6635477 | 0.77 | MPO (0.63) | SMN1; SMN2RAB9ATAAR1ALDH1A1LMNA | |
| SCHEMBL2093615 | 0.77 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9ATAAR1ALDH1A1HTT | |
| SCHEMBL6029973 | 0.77 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9APOLBTAAR1ALDH1A1 | |
| SCHEMBL29451530 | 0.75 | ALDH1A1 (0.50) | SMN1; SMN2RAB9ANPC1POLBALDH1A1 | |
| SCHEMBL18381293 | 0.75 | KMT2A (0.55) | SMN1; SMN2RAB9ANPC1POLBALDH1A1 | |
| SCHEMBL1694984 | 0.75 | RAB9A (0.62) | SMN1; SMN2RAB9ANPC1TAAR1ALDH1A1 | |
| SCHEMBL9090227 | 0.74 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9APOLBALDH1A1HTT | |
| SCHEMBL9779435 | 0.74 | KMT2A (0.60) | SMN1; SMN2RAB9APOLBTAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313396-B1 | G PROTEIN-COUPLED RECEPTOR KINASE INHIBITORS AND METHODS FOR USE OF THE SAME | UNIV MICHIGAN REGENTS (US) | 2021-12-15 | — | — | EP | disclosed |
| WO-2021046225-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2021-03-11 | — | — | WO | disclosed |