Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 8/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23083349 | 0.83 | TAAR1 (0.54) | TAAR1LMNACA1CA2LTA4H | |
| SCHEMBL10041803 | 0.79 | MPO (0.53) | MPOSLC6A4TAAR1CA2 | |
| SCHEMBL7655723 | 0.78 | HTT (0.60) | TAAR1LMNACA1CA2LTA4H | |
| SCHEMBL27586477 | 0.78 | MTNR1A (0.52) | MPOSMN1; SMN2 | |
| SCHEMBL32665565 | 0.78 | AANAT (0.60) | MPOSLC6A4TAAR1CA2 | |
| SCHEMBL23083248 | 0.77 | SMN1; SMN2 (0.52) | TAAR1LMNASMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL7866223 | 0.76 | CNR1 (0.54) | MPOTAAR1CA1CA2SMN1; SMN2 | |
| SCHEMBL14241867 | 0.76 | TAAR1 (0.56) | TAAR1CNR1RAB9A | |
| Hydrochloric Acid SCHEMBL327794 | 0.76 | AKR1B1 (0.52) | MPOTAAR1LMNACA1CA2 | |
| SCHEMBL5309632 | 0.75 | MPO (0.56) | MPOSLC6A4TAAR1CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412363-A1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS | Neurocrine Biosciences, Inc. (US) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003011870-A1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS | NEUROCRINE BIOSCIENCES, INC. (US) | 2003-02-13 | — | — | WO | disclosed |