SCHEMBL23087142

SCHEMBL23087142

CC(C)c1cccc(C(C)C)c1N1CCN(c2c(C(C)C)cccc2C(C)C)C1=P(C1CCCCC1)(C1CCCCC1)C1CCCCC1.[Ru]

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.31
DPP4 P27487 2/20 0.31
ROCK2 O75116 1/20 0.31
FAAH O00519 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
GABRA1 P14867 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
PTGS1 P23219 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17836910 0.85
SCHEMBL28448171 0.84
SCHEMBL4013986 0.78 CHRNB2 (0.31)
SCHEMBL23087150 0.73 ALDH1A1 (0.35)
SCHEMBL18179635 0.69 SIGMAR1 (0.42) ANPEPDPP4FAAHCA1CA2
SCHEMBL23087141 0.69 ANPEP (0.30) ANPEPDPP4
SCHEMBL12474244 0.69 GABRA1 (0.40) ANPEPDPP4FAAHCA1CA2
SCHEMBL22749140 0.69 GABRA1 (0.40) ANPEPDPP4FAAHCA1CA2
SCHEMBL13258747 0.69 GABRA1 (0.40) ANPEPDPP4FAAHCA1CA2
SCHEMBL29189781 0.69 GABRA1 (0.40) ANPEPDPP4FAAHCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11291983-B2 Organoruthenium carbide complexes as precatalysts for olefin metathesis APEIRON SYNTHESIS S.A. (PL) 2022-04-05 US claimed
US-20210077988-A1 ORGANORUTHENIUM CARBIDE COMPLEXES AS PRECATALYSTS FOR OLEFIN METATHESIS Apeiron Synthesis S. A. (PL) 2021-03-18 US claimed
WO-2023158768-A1 DUAL CATALYST SYSTEM FOR MASS ROMP AND CATIONIC POLYMERIZABLE COMPOSITIONS PROMERUS, LLC (US) 2023-08-24 WO disclosed
US-11554365-B2 Organoruthenium carbide complexes as precatalysts for olefin metathesis APEIRON SYNTHESIS S.A. (PL) 2023-01-17 US disclosed
US-20220176362-A1 ORGANORUTHENIUM CARBIDE COMPLEXES AS PRECATALYSTS FOR OLEFIN METATHESIS Apeiron Synthesis S. A. (PL) 2022-06-09 US disclosed
US-11291983-B2 Organoruthenium carbide complexes as precatalysts for olefin metathesis APEIRON SYNTHESIS S.A. (PL) 2022-04-05 US disclosed
US-20210077988-A1 ORGANORUTHENIUM CARBIDE COMPLEXES AS PRECATALYSTS FOR OLEFIN METATHESIS Apeiron Synthesis S. A. (PL) 2021-03-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11554365-B2 Organoruthenium carbide complexes as precatalysts for olefin metathesis RCOR1, NFE2L2, ARL1 ANPEP 4699/4885DPP4 4709/4885ROCK2 1075/4885
US-20220176362-A1 ORGANORUTHENIUM CARBIDE COMPLEXES AS PRECATALYSTS FOR OLEFIN METATHESIS RCOR1, NFE2L2, ARL1 ANPEP 4699/4885DPP4 4709/4885ROCK2 1075/4885
US-20210077988-A1 ORGANORUTHENIUM CARBIDE COMPLEXES AS PRECATALYSTS FOR OLEFIN METATHESIS RCOR1, OXER1, ARL1 ANPEP 4705/4885DPP4 4699/4885ROCK2 1118/4885
US-11291983-B2 Organoruthenium carbide complexes as precatalysts for olefin metathesis RCOR1, OXER1, ARL1 ANPEP 4705/4885DPP4 4699/4885ROCK2 1118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.