Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.56 |
| ▸ | CA1 | P00915 | 9/20 | 0.56 |
| ▸ | CA9 | Q16790 | 6/20 | 0.56 |
| ▸ | CA12 | O43570 | 4/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.51 |
| ▸ | SCD | O00767 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4802122 | 0.84 | CA2 (0.55) | CA2CA1CA9CA12CA4 | |
| SCHEMBL4802143 | 0.79 | PTGS1 (0.73) | CA2CA1CA9CA12CA4 | |
| SCHEMBL14161390 | 0.79 | CA1 (0.55) | CA2CA1CA9CA12CA4 | |
| SCHEMBL30269814 | 0.78 | CA2 (0.49) | CA2CA1CA9CA12CA4 | |
| SCHEMBL301718 | 0.76 | CA2 (0.69) | CA2CA1CA9CA12CA4 | |
| SCHEMBL20506958 | 0.75 | CA1 (0.46) | CA2CA1CA9CA12CA4 | |
| SCHEMBL6135419 | 0.75 | TDP2 (0.61) | CA2CA1CA9CA12LMNA | |
| SCHEMBL2568298 | 0.75 | ALOX5AP (0.49) | CA2CA1CA9CA12CA4 | |
| SCHEMBL28299345 | 0.74 | CA2 (0.67) | CA2CA1CA9CA12CA4 | |
| SCHEMBL28833280 | 0.74 | PTGS2 (0.47) | PTGS1PTGS2SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349990-A1 | ARYL-PHENYL-SULFONAMIDE-PHENYLENE COMPOUNDS AND THEIR USE | Pimco 2664 Limited (GB) | 2011-08-03 | — | — | EP | disclosed |