Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.47 |
| ▸ | SCD | O00767 | 2/20 | 0.47 |
| ▸ | FADS1 | O60427 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23693717 | 0.89 | PTGS2 (0.46) | PTGS2SCDFADS1ENPP2 | |
| SCHEMBL29886981 | 0.89 | PTGS2 (0.46) | PTGS2SCDFADS1ENPP2 | |
| SCHEMBL3875536 | 0.81 | LMNA (0.53) | PTGS2SCDFADS1 | |
| SCHEMBL4941551 | 0.78 | PTGS2 (0.48) | PTGS2SCDFADS1MEN1NPC1 | |
| SCHEMBL9206986 | 0.75 | PTGS2 (0.73) | PTGS2SCDFADS1PTGS1 | |
| SCHEMBL28022700 | 0.75 | PTGS2 (0.51) | PTGS2SCDFADS1 | |
| SCHEMBL8548523 | 0.75 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL355740 | 0.74 | ENPP2 (0.50) | PTGS2ENPP2 | |
| SCHEMBL309902 | 0.74 | SCD (0.45) | PTGS2SCDFADS1PTGS1ENPP2 | |
| SCHEMBL28971540 | 0.74 | ALDH1A1 (0.43) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981251-B | Dibenzofuran derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114981251-A | Diphenyl furan derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-08-30 | — | — | CN | disclosed |