Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 7/20 | 0.64 |
| ▸ | CTSB | P07858 | 4/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSH | P09668 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641489 | 0.91 | CTSB (0.55) | PSMB5CTSBCTSLCAPN1CMA1 | |
| SCHEMBL9642155 | 0.86 | CTSK (0.59) | PSMB5CTSBCTSKCTSLCTSH | |
| SCHEMBL20204723 | 0.85 | CTSB (0.63) | PSMB5CTSBCTSLCMA1CTRC | |
| SCHEMBL5572956 | 0.85 | CTSB (0.63) | PSMB5CTSBCTSLCMA1CTRC | |
| SCHEMBL20204725 | 0.85 | CTSB (0.63) | PSMB5CTSBCTSLCMA1CTRC | |
| SCHEMBL13706577 | 0.82 | CTSB (0.61) | PSMB5CTSBCTSLCMA1CTRC | |
| SCHEMBL7144589 | 0.82 | CTSB (0.61) | PSMB5CTSBCTSLCMA1CTRC | |
| SCHEMBL8259852 | 0.81 | CTSB (0.62) | PSMB5CTSBCTSLCMA1CTRC | |
| SCHEMBL13933704 | 0.81 | CTSB (0.62) | PSMB5CTSBCTSKCTSLCAPN1 | |
| SCHEMBL10890377 | 0.81 | FAAH (0.60) | PSMB5CTSBCTSKFAAHCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11241398-B2 | Affinity medicant conjugate | AF CHEMICALS, LLC (US) | 2022-02-08 | — | — | US | disclosed |
| US-11135182-B2 | Affinity medicant conjugates | AF CHEMICALS, LLC (US) | 2021-10-05 | — | — | US | disclosed |
| US-20210077425-A1 | AFFINITY MEDICANT CONJUGATE | AF CHEMICALS, LLC (US) | 2021-03-18 | — | — | US | disclosed |