Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23094258 | 0.89 | L3MBTL1 (0.70) | TP53ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL23094211 | 0.84 | ALDH1A1 (0.86) | ALDH1A1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23094291 | 0.84 | TP53 (1.00) | TP53ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL21467750 | 0.82 | CYP3A4 (0.64) | TP53ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL23094206 | 0.81 | ALDH1A1 (0.79) | ALDH1A1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23094309 | 0.80 | TDP1 (1.00) | TP53ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL23094158 | 0.80 | MAPT (0.70) | TP53ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL23094207 | 0.80 | TDP1 (0.78) | ALDH1A1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23094227 | 0.79 | CYP3A4 (1.00) | TP53ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL23094156 | 0.78 | TDP1 (1.00) | ALDH1A1TDP1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947188-B2 | Small molecule ferroptosis inducers | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947188-B2 | Small molecule ferroptosis inducers | GPX4, AIFM2, GPX1 | TP53 1242/4885ALDH1A1 845/4885TDP1 4664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.