Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14027773 | 0.81 | CHRNB2 (0.33) | — | |
| SCHEMBL22800208 | 0.79 | — | — | |
| SCHEMBL21439942 | 0.79 | MAPT (0.37) | PIK3CA | |
| SCHEMBL21604588 | 0.77 | OGA (0.37) | PIK3CA | |
| SCHEMBL18824669 | 0.76 | PIK3CA (0.38) | GAAL3MBTL1PIK3CA | |
| SCHEMBL7919451 | 0.75 | CHRM4 (0.44) | GAAL3MBTL1PIK3CA | |
| SCHEMBL19054141 | 0.72 | NOS2 (0.40) | GAAL3MBTL1PIK3CA | |
| SCHEMBL14871075 | 0.71 | HTR3A (0.46) | GAAL3MBTL1PIK3CA | |
| SCHEMBL12915444 | 0.69 | NOS3 (0.33) | — | |
| SCHEMBL22725554 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3371174-B1 | INDOLIN-2-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2021-03-17 | — | — | EP | disclosed |