SCHEMBL7919451

SCHEMBL7919451

Cc1ccc2oc(C)nc2n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRM3 P20309 1/20 0.44
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44
CHRNA7 P36544 1/20 0.44
HTR3A P46098 1/20 0.44
KCNH2 Q12809 1/20 0.44
GAA P10253 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
RAB9A P51151 3/20 0.37
CCR1 P32246 2/20 0.37
CCR5 P51681 1/20 0.37
KMT2A Q03164 2/20 0.34
PIK3CA P42336 1/20 0.34
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
NPC1 O15118 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31507012 0.78 CHRM4 (0.42) CHRM4CHRM5CHRM1CHRM3CHRNB4
SCHEMBL6008921 0.78 CHRM4 (0.42) CHRM4CHRM5CHRM1CHRM3CHRNB4
SCHEMBL18824669 0.78 PIK3CA (0.38) GAAL3MBTL1RAB9AKMT2APIK3CA
SCHEMBL19054141 0.78 NOS2 (0.40) GAAL3MBTL1RAB9APIK3CANOS1
SCHEMBL18645383 0.78 CHRM4 (0.42) CHRM4CHRM5CHRM1CHRM3CHRNB4
SCHEMBL4700942 0.77 TDP1 (0.46) CHRM4CHRM5CHRM1CHRM3CHRNB4
SCHEMBL14871075 0.77 HTR3A (0.46) HTR3AKCNH2GAAL3MBTL1RAB9A
SCHEMBL23097041 0.75 GAA (0.35) GAAL3MBTL1PIK3CA
SCHEMBL21604478 0.75 CHRM4 (0.40) CHRM4CHRM5CHRM1CHRM3CHRNB4
SCHEMBL12910354 0.75 NPC1 (0.47) CHRM4CHRM5CHRM1CHRM3CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11818932-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
US-20230295114-A1 AKT3 MODULATORS Georgiamune Inc. 2023-09-21 US disclosed
US-20230295114-A1 AKT3 MODULATORS Georgiamune Inc. 2023-09-21 US disclosed
US-11706973-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-18 US disclosed
US-11696496-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 US disclosed
US-11696499-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 US disclosed
US-11696499-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 US disclosed
US-11696491-B2 Organometallic compound, organic light-emitting device including the same and apparatus including the organometallic compound SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 US disclosed
US-11678498-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-13 US disclosed
US-11678498-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-13 US disclosed
US-20120142714-A1 BICYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-06-07 US disclosed
US-20120142714-A1 BICYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-06-07 US disclosed
WO-2012074126-A1 BICYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-06-07 WO disclosed
US-20120010247-A1 BICYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-01-12 US disclosed
US-20120010247-A1 BICYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-01-12 US disclosed
WO-2011136385-A1 BICYCLIC COMPOUND DERIVATIVES AND THEIR USE AS ACC INHIBITORS. TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-11-03 WO disclosed
US-20110263562-A1 BICYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-10-27 US disclosed
US-20110263562-A1 BICYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-10-27 US disclosed
EP-2351743-A1 BICYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2011-08-03 EP disclosed
WO-2010050445-A1 BICYCLIC COMPOUND 武田薬品工業株式会社 (JP) 2010-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295114-A1 AKT3 MODULATORS AKT3, AKT2, MTOR CHRM4 4614/4885CHRM5 4752/4885CHRM1 4480/4885
US-20120010247-A1 BICYCLIC COMPOUND ACACA, CPT1B, ACACB CHRM4 3106/4885CHRM5 1630/4885CHRM1 2336/4885
US-11706973-B2 Condensed cyclic compound and organic light-emitting device including the same C1S, CCNT1, C9 CHRM4 64/4885CHRM5 94/4885CHRM1 4/4885
US-20110263562-A1 BICYCLIC COMPOUND ACACA, CPT1B, ACACB CHRM4 2442/4885CHRM5 1287/4885CHRM1 1615/4885
US-20120142714-A1 BICYCLIC COMPOUND ACACA, ACACB, FABP4 CHRM4 3937/4885CHRM5 3987/4885CHRM1 3934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.