Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH1 | Q13686 | 13/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26527717 | 0.88 | ALKBH1 (0.36) | ALKBH1AKT1AKT2GPR139EGLN1 | |
| SCHEMBL23099412 | 0.78 | POLB (0.33) | ALKBH1LMNAPOLB | |
| SCHEMBL26527673 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1MEN1LMNAMAPT | |
| SCHEMBL23099556 | 0.70 | KDM4E (0.33) | AKT1AKT2KDM4EALDH1A1MEN1 | |
| SCHEMBL23099492 | 0.69 | GABRP (0.32) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL23099456 | 0.69 | AGBL2 (0.34) | GPR139MEN1KMT2ANPC1RAB9A | |
| SCHEMBL23099503 | 0.67 | GAA (0.50) | KDM4EALDH1A1MEN1LMNAMAPT | |
| SCHEMBL23099499 | 0.65 | MTNR1B (0.44) | KDM4EALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL26527736 | 0.64 | KDM4E (0.40) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL24689506 | 0.63 | GABRP (0.34) | KDM4EALDH1A1MEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021048342-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2021-03-18 | — | — | WO | disclosed |