Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 13/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23112288 | 0.80 | GRIN2B (0.46) | HSD11B1GRIN2BPOLB | |
| SCHEMBL23112649 | 0.79 | HSD11B1 (0.39) | HSD11B1MEN1KMT2AGRIN2B | |
| SCHEMBL23382084 | 0.77 | RORC (0.48) | MEN1KMT2A | |
| SCHEMBL23112760 | 0.73 | LMNA (0.42) | MEN1KMT2APOLB | |
| SCHEMBL23112641 | 0.72 | HSD11B1 (0.35) | HSD11B1MEN1KMT2AGRIN2BCCR2 | |
| SCHEMBL23091877 | 0.72 | HRH3 (0.40) | — | |
| SCHEMBL3541960 | 0.71 | DRD2 (0.49) | HSD11B1 | |
| SCHEMBL31687677 | 0.70 | HSD11B1 (0.45) | HSD11B1MEN1KMT2APOLB | |
| SCHEMBL14471924 | 0.70 | CA12 (0.46) | MEN1KMT2APOLB | |
| SCHEMBL4725181 | 0.70 | OPRM1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793559-A1 | SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2021-03-24 | — | — | EP | disclosed |