Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729583 | 0.84 | RBP4 (0.41) | GAAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL22729640 | 0.82 | CYP46A1 (0.41) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL22729426 | 0.81 | RIPK1 (0.47) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL22729699 | 0.81 | NAAA (0.43) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL29839302 | 0.81 | RIPK1 (0.47) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL22729839 | 0.81 | ALDH1A1 (0.43) | GAAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL22729528 | 0.80 | EPHX2 (0.42) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL22729684 | 0.79 | SPR (0.44) | GAAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL22729412 | 0.79 | SCD (0.50) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL23116376 | 0.79 | KDM4E (0.46) | GAAALDH1A1HSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-10-04 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | GBA1, GBA2, GALC | GAA 4/4885ALDH1A1 2626/4885HSD17B10 1790/4885 |
| US-11459325-B2 | Heterocyclic compound | GBA1, GBA2, GALC | GAA 4/4885ALDH1A1 2660/4885HSD17B10 1691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.