Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | PTPRA | P18433 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23118150 | 1.00 | ALDH1A1 (0.37) | ALDH1A1OR51E2KMOPTPRA | |
| SCHEMBL28420763 | 0.80 | XPO1 (0.33) | ALDH1A1 | |
| SCHEMBL23139095 | 0.80 | XPO1 (0.33) | ALDH1A1 | |
| SCHEMBL20703189 | 0.76 | ALDH1A1 (0.39) | ALDH1A1OR51E2KMOPTPRA | |
| SCHEMBL20703191 | 0.76 | ALDH1A1 (0.39) | ALDH1A1OR51E2KMOPTPRA | |
| SCHEMBL11518836 | 0.72 | CXCR3 (0.34) | — | |
| SCHEMBL23118092 | 0.72 | GABRD (0.34) | ALDH1A1OR51E2KMOPTPRA | |
| SCHEMBL23118091 | 0.72 | GABRD (0.34) | ALDH1A1OR51E2KMOPTPRA | |
| SCHEMBL23118122 | 0.69 | NLRP3 (0.40) | KMO | |
| SCHEMBL23118112 | 0.69 | ALDH1A1 (0.37) | ALDH1A1OR51E2KMOPTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3661921-B1 | SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME | NODTHERA LTD (GB) | 2023-10-18 | — | — | EP | disclosed |
| US-20210087147-A1 | SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME | NodThera Limited (GB) | 2021-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087147-A1 | SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME | NLRP3, NOD1, NLRP1 | ALDH1A1 961/4885OR51E2 4592/4885KMO 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.