Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23134748 | 0.90 | PDE4B (0.40) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL21409284 | 0.89 | NR3C1 (0.42) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL23123147 | 0.88 | HSD11B1 (0.37) | HSD11B1CRBNNPSR1 | |
| SCHEMBL23121734 | 0.87 | HSD11B1 (0.38) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| Trifluoroacetic Acid SCHEMBL30009630 | 0.84 | PKM (0.40) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL23134536 | 0.83 | NR3C1 (0.42) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL23123241 | 0.83 | DDB1 (0.40) | HSD11B1LMNAALDH1A1CRBNMEN1 | |
| SCHEMBL31255390 | 0.83 | GAA (0.44) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL21409448 | 0.83 | HSD11B1 (0.42) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL30501253 | 0.82 | NR3C1 (0.49) | NR3C1PGRSLC6A4KCNH2PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114641473-A | BRD9 bifunctional degradation agent and use method thereof | 诺华股份有限公司 | 2022-06-17 | — | — | CN | disclosed |
| WO-2021055295-A1 | BRD9 BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2021-03-25 | — | — | WO | disclosed |