Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NQO2 | P16083 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008562 | 0.83 | ACLY (0.45) | HTR6BRD4ATAD2MEN1KMT2A | |
| SCHEMBL2010391 | 0.77 | HTR6 (0.43) | HTR6POLBHTR1ADRD2HTR7 | |
| SCHEMBL2314057 | 0.71 | FABP4 (0.47) | HTR6BRD4ATAD2MEN1KMT2A | |
| SCHEMBL2008761 | 0.61 | HTR6 (0.44) | HTR6NQO2DRD2HTR2AHTR7 | |
| SCHEMBL2013322 | 0.60 | HTR6 (0.49) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL3421479 | 0.60 | TERT (0.53) | BRD4ATAD2MEN1KMT2AALDH1A1 | |
| SCHEMBL2006265 | 0.60 | KCNH2 (0.48) | HTR6NQO2HTR1ADRD2HTR7 | |
| SCHEMBL2312698 | 0.60 | HTR6 (0.50) | HTR6MEN1KMT2ANQO2POLB | |
| SCHEMBL2007979 | 0.59 | NQO2 (0.42) | HTR6NQO2KDM4EALDH1A1HTR1A | |
| SCHEMBL2006908 | 0.59 | HTR6 (0.51) | HTR6HTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200980-B1 | AMINO ARYLSULFONAMIDE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS FIELD OF INVENTION | SUVEN LIFE SCIENCES LTD (IN) | 2011-08-03 | — | — | EP | claimed |