Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1860384 | 0.87 | APP (0.41) | PTPN1PTPN11RARBLMNAMAPT | |
| SCHEMBL1859370 | 0.86 | TP53 (0.39) | PTPN1PTPN11RAB9ARARBLMNA | |
| Dimethylamine SCHEMBL1865125 | 0.86 | PTPN11 (0.40) | PTPN1PTPN11RARBLMNAMAPT | |
| SCHEMBL1861533 | 0.85 | KDM4E (0.43) | GCGRMAPK14 | |
| Dimethylamine SCHEMBL1860131 | 0.84 | PTPN11 (0.40) | PTPN1PTPN11RAB9ALMNAMAPT | |
| SCHEMBL1864510 | 0.84 | ALDH1A1 (0.41) | PTPN1 | |
| SCHEMBL1855908 | 0.80 | LTA4H (0.38) | PTPN1PTPN11LMNAMAPTMEN1 | |
| Dimethylamine SCHEMBL1860477 | 0.76 | PTPN11 (0.38) | PTPN11CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL1858617 | 0.75 | SLC6A4 (0.34) | PTPN11SLC6A3LTA4HCYP1A2CYP19A1 | |
| SCHEMBL588822 | 0.75 | NR5A1 (0.43) | NPC1RAB9ARARBMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558616-B2 | MESO-SUBSTITUTED PORPHYRINS | MOLTENI & C (IT) | 2011-08-24 | — | — | EP | claimed |
| JP-4751068-B2 | — | — | 2011-08-17 | — | — | JP | claimed |
| EP-1558616-B1 | MESO-SUBSTITUTED PORPHYRINS | MOLTENI & C (IT) | 2008-02-27 | — | — | EP | claimed |
| US-20060040914-A1 | Meso-substituted porphyrins | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) | 2006-02-23 | — | — | US | claimed |
| EP-1558616-A2 | MESO-SUBSTITUTED PORPHYRINS | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO SOCIETA' PER AZIONI (IT) | 2005-08-03 | — | — | EP | claimed |
| WO-2004035590-A2 | MESO-SUBSTITUTED PORPHYRINS | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A (IT) | 2004-04-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040914-A1 | Meso-substituted porphyrins | PPOX, PPIF, ALAD | PTPN1 1494/4885PTPN11 1686/4885NPC1 2445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.