Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 3/20 | 0.82 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.82 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.69 |
| ▸ | GSK3B | P49841 | 3/20 | 0.62 |
| ▸ | BACE1 | P56817 | 2/20 | 0.62 |
| ▸ | VCP | P55072 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | FOS | P01100 | 1/20 | 0.56 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20585522 | 1.00 | JUN (0.82) | JUNNFKB1HDAC1HDAC2HDAC8 | |
| SCHEMBL19534824 | 0.94 | GSK3B (0.72) | JUNNFKB1HDAC1HDAC2HDAC8 | |
| SCHEMBL3207347 | 0.90 | NFKB1 (1.00) | JUNNFKB1VCPKDM4EALDH1A1 | |
| SCHEMBL3207352 | 0.90 | NFKB1 (1.00) | JUNNFKB1VCPKDM4EALDH1A1 | |
| Dimethylcurcumin SCHEMBL3487105 | 0.90 | HDAC1 (0.78) | JUNNFKB1HDAC1HDAC2HDAC8 | |
| Dimethylcurcumin SCHEMBL29354872 | 0.90 | HDAC1 (0.78) | JUNNFKB1HDAC1HDAC2HDAC8 | |
| Dimethylcurcumin SCHEMBL3686107 | 0.90 | HDAC1 (0.78) | JUNNFKB1HDAC1HDAC2HDAC8 | |
| Dimethylcurcumin SCHEMBL3487103 | 0.90 | HDAC1 (0.78) | JUNNFKB1HDAC1HDAC2HDAC8 | |
| SCHEMBL20414392 | 0.88 | GSK3B (0.76) | JUNNFKB1HDAC1HDAC2HDAC8 | |
| SCHEMBL111271 | 0.86 | JUN (0.81) | JUNNFKB1VCPKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11117907-B2 | Curcuminoid-inspired synthetic compounds as anti-tumor agents | UNIVERSITY OF NORTH FLORIDA BOARD OF TRUSTEES (US) | 2021-09-14 | — | — | US | disclosed |
| US-20210087208-A1 | NOVEL CURCUMINOID-INSPIRED SYNTHETIC COMPOUNDS AS ANTI-TUMOR AGENTS | UNIVERSITY OF NORTH FLORIDA BOARD OF TRUSTEES (US) | 2021-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11117907-B2 | Curcuminoid-inspired synthetic compounds as anti-tumor agents | FOXO3, IKZF3, FOXO1 | JUN 543/4885NFKB1 136/4885HDAC1 265/4885 |
| US-20210087208-A1 | NOVEL CURCUMINOID-INSPIRED SYNTHETIC COMPOUNDS AS ANTI-TUMOR AGENTS | IKZF3, FOXO3, FOXO1 | JUN 457/4885NFKB1 96/4885HDAC1 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.