SCHEMBL111271

SCHEMBL111271

COc1cc(/C=C/C(=O)O)ccc1OC(C)=O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JUN P05412 1/20 0.81
NFKB1 P19838 1/20 0.81
KDM4E B2RXH2 4/20 0.79
ALDH1A1 P00352 3/20 0.79
HPGD P15428 2/20 0.79
HSD17B10 Q99714 2/20 0.79
ALOX15 P16050 1/20 0.79
MAPK1 P28482 1/20 0.79
SMN1; SMN2 Q16637 1/20 0.79
SNCA P37840 2/20 0.66
PKM P14618 2/20 0.66
CA12 O43570 1/20 0.66
CA1 P00915 1/20 0.66
CA2 P00918 1/20 0.66
CA3 P07451 1/20 0.66
CSNK2A2 P19784 1/20 0.66
CA4 P22748 1/20 0.66
CA6 P23280 1/20 0.66
CA5A P35218 1/20 0.66
CA7 P43166 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL111272 1.00 JUN (0.81) JUNNFKB1KDM4EALDH1A1HPGD
SCHEMBL29988654 1.00 JUN (0.81) JUNNFKB1KDM4EALDH1A1HPGD
SCHEMBL716467 1.00 JUN (0.81) JUNNFKB1KDM4EALDH1A1HPGD
SCHEMBL29988606 1.00 JUN (0.81) JUNNFKB1KDM4EALDH1A1HPGD
Hydrochloric Acid SCHEMBL8830791 0.98 JUN (0.78) JUNNFKB1KDM4EALDH1A1HPGD
Acetamide SCHEMBL10706949 0.96 KDM4E (0.78) JUNNFKB1KDM4EALDH1A1HPGD
SCHEMBL2260497 0.94 KDM4E (0.79) JUNNFKB1KDM4EALDH1A1HPGD
SCHEMBL2260502 0.94 KDM4E (0.79) JUNNFKB1KDM4EALDH1A1HPGD
SCHEMBL8620254 0.93 JUN (0.71) JUNNFKB1KDM4EALDH1A1HPGD
SCHEMBL8620256 0.93 JUN (0.71) JUNNFKB1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220402930-A1 USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS PRG S&TECH INC. (KR) 2022-12-22 US claimed
EP-4056573-A1 USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS PRG S&Tech Inc. (KR) 2022-09-14 EP claimed
CN-114929711-A Use of novel compounds for preventing, ameliorating or treating amyotrophic lateral sclerosis PRG科技株式会社 2022-08-19 CN claimed
WO-2021086101-A1 USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS (주)피알지에스앤텍 2021-05-06 WO claimed
US-20130345454-A2 A PROCESS FOR THE PREPARATION OF PHYTOSTERYL FERULATE COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-12-26 US claimed
WO-2010097810-A2 A PROCESS FOR THE PREPARATION OF PHYTOSTERYL FERULATE COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2010-09-02 WO claimed
EP-0166542-B1 TRITERPENYL ESTERS OF ORGANIC ACIDS, PROCESS FOR THEIR PRODUCTION, AND HYPOLIPIDEMIC AGENTS COMPOSED OF THEM AMANO PHARMACEUTICAL CO., LTD. (JP) 1990-08-08 EP claimed
US-4748161-A Triterpenyl esters of organic acids and hypolipidemic agents composed of them AMANO PHARMACEUTICAL CO., LTD. (JP) 1988-05-31 US claimed
EP-0166542-A2 Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them AMANO PHARMACEUTICAL CO., LTD. (JP) 1986-01-02 EP claimed
US-20250214924-A1 NOVEL COMPOUNDS AND USES THEREOF ACTIVON CO.,LTD. (KR) 2025-07-03 US disclosed
US-12292665-B2 Bistable liquid crystal dispersion devices comprising metal-organic mesogens and applications thereof GAUZY LTD. (IL) 2025-05-06 US disclosed
EP-4471003-A1 NOVEL COMPOUND AND USE THEREOF Activon Co., Ltd. (KR) 2024-12-04 EP disclosed
CN-119032076-A Novel compounds and uses thereof 株式会社安提昂 2024-11-26 CN disclosed
US-20240189268-A1 SESQUITERPENE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND USE THEREOF MFC CO., LTD. (KR) 2024-06-13 US disclosed
US-4038200-A LYOTROPIC NEMATIC LIQUID CRYSTALS FOR USE IN ELECTRO-OPTICAL DISPLAY DEVICES TEXAS INSTRUMENTS INCORPORATED (US) 1977-07-26 US disclosed
US-4038199-A LYOTROPIC NEMATIC LIQUID CRYSTALS FOR USE IN ELECTRO-OPTICAL DISPLAY DEVICES TEXAS INSTRUMENTS INCORPORATED (US) 1977-07-26 US disclosed
US-4014920-A N-cinnamylcarbamic acid esters CIBA-GEIGY CORPORATION (US) 1977-03-29 US disclosed
US-4005928-A Nematic liquid crystal displays for low voltage direct current operation TEXAS INSTRUMENTS INCORPORATED (US) 1977-02-01 US disclosed
US-3965030-A BENZYLIDENEAMINES TEXAS INSTRUMENTS INCORPORATED (US) 1976-06-22 US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130345454-A2 A PROCESS FOR THE PREPARATION OF PHYTOSTERYL FERULATE SOAT1, CYP46A1, DHCR7 JUN 2461/4885NFKB1 916/4885KDM4E 1886/4885
US-20250214924-A1 NOVEL COMPOUNDS AND USES THEREOF GPX1, GPX4, PRDX3 JUN 2316/4885NFKB1 1895/4885KDM4E 649/4885
US-20220402930-A1 USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS SOD1, SLC75A1, SLC43A1 JUN 3245/4885NFKB1 2099/4885KDM4E 4446/4885
US-20240189268-A1 SESQUITERPENE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND USE THEREOF MSTN, MYOF, MBNL1 JUN 3022/4885NFKB1 1052/4885KDM4E 1622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.