Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15456785 | 0.88 | MAPT (0.42) | HSD17B10POLBALDH1A1KDM4EMEN1 | |
| SCHEMBL14632151 | 0.88 | MAPT (0.42) | HSD17B10TSHRPOLBALDH1A1KDM4E | |
| SCHEMBL2742310 | 0.83 | TSHR (0.67) | HSD17B10TSHRPOLBALDH1A1KDM4E | |
| SCHEMBL2742309 | 0.83 | TSHR (0.57) | HSD17B10TSHRPOLBALDH1A1KDM4E | |
| SCHEMBL231034 | 0.82 | ALDH1A1 (0.55) | HSD17B10TSHRPOLBALDH1A1KDM4E | |
| SCHEMBL12329664 | 0.82 | ALDH1A1 (0.55) | HSD17B10TSHRPOLBALDH1A1KDM4E | |
| SCHEMBL2742308 | 0.81 | ALDH1A1 (0.59) | HSD17B10TSHRPOLBALDH1A1KDM4E | |
| SCHEMBL14937791 | 0.77 | ALDH1A1 (0.51) | HSD17B10TSHRPOLBALDH1A1KDM4E | |
| SCHEMBL231558 | 0.76 | ELANE (0.66) | ELANE | |
| SCHEMBL14937838 | 0.76 | ALDH1A1 (0.50) | HSD17B10TSHRPOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210122713-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2021-04-29 | — | — | US | claimed |
| EP-3672960-A2 | COMPOUNDS, SALTS THEREOF AND THEIR USE FOR THE TREATMENT OF DISEASES | Acadia Pharmaceuticals Inc. (US) | 2020-07-01 | — | — | EP | claimed |
| WO-2019040104-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | claimed |
| US-20020198376-A1 | Novel urea derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-26 | — | — | US | claimed |
| US-6492370-B1 | Urea derivatives and pharmaceutical compositions thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-10 | — | — | US | claimed |
| CN-1299344-A | Novel urea derivatives | SANTEN PHARCEUMATICAL CO LTD (JP) | 2001-06-13 | — | — | CN | claimed |
| EP-1072591-A1 | NOVEL UREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-01-31 | — | — | EP | claimed |
| US-6030978-A | EXHIBIT FUNGICIDAL EFFECT OR GROWTH-INHIBITORY EFFECT AGAINST FUNGI INCLUDING CUTANEOUS FILAMENTOUS FUNGUS, SUCH AS EPIDERMOPHYTON, MICROSPORUM, TRICHOPHYTON, SPOROTHRIX SCHENCKII, ASPERGILLUS OR CANDIDA; NONTOXICITY; | HANWHA CORPORATION (KR) | 2000-02-29 | — | — | US | claimed |
| US-6008356-A | BRBERINE SALT DERIVATIVE IS REACTED WITH SODIUM TETRABORATE AND POTASSIUM CARBONATE IN ALCOHOL SOLVEANT TO FORM INTERMEDIATE, REACTING INTERMEDIATE WITH ALKYL SUBSTITUENT IN ACETONITRILE SOLVENT, OXIDIZING THE FORMED INTERMEDIATE | HANWHA CORPORATION (KR) | 1999-12-28 | — | — | US | claimed |
| US-5998468-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS; ANTICANCER AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-12-07 | — | — | US | claimed |
| US-5922759-A | Butenolide endothelin antagonists | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | claimed |
| US-5691373-A | TREATING SUBARACHNOID HEMORRHAGE | WARNER-LAMBERT COMPANY (US) | 1997-11-25 | — | — | US | claimed |
| WO-1997037986-A1 | ENDOTHELIN ANTAGONISTS WITH ETHER-LINKED GROUPS | WARNER-LAMBERT COMPANY (US) | 1997-10-16 | — | — | WO | claimed |
| WO-1997008169-A1 | FURANONE ENDOTHELIN ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-03-06 | — | — | WO | claimed |
| WO-1997002265-A1 | BUTENOLIDE ENDOTHELIN ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-01-23 | — | — | WO | claimed |
| EP-0714391-A1 | SUBSTITUTED 2(5H)FURANONE, 2(5H)THIOPHENONE AND 2(5H)PYRROLONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ENDOTHELIN ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1996-06-05 | — | — | EP | claimed |
| WO-1995005376-A1 | SUBSTITUTED 2(5H)FURANONE, 2(5H)THIOPHENONE AND 2(5H)PYRROLONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ENDOTHELIN ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-02-23 | — | — | WO | claimed |
| US-4895586-A | PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1990-01-23 | — | — | US | claimed |
| EP-4211146-A1 | SYNTHETIC CYCLIC PEPTIDE MIMETICS | Bar Ilan University (IL) | 2023-07-19 | — | — | EP | disclosed |
| US-4105668-A | 6-AMINO-2,2-DIMETHYL-3-(1 -SUBSTITUTED TETRAZOL-5-YL)PENAM COMPOUND REACTED WITH HYDROGEN FLUORIDE | PFIZER INC. (US) | 1978-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122713-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | SLC10A1, VHL, CYP11B2 | HSD17B10 382/4885TSHR 2043/4885POLB 1110/4885 |
| US-20020198376-A1 | Novel urea derivatives | TNF, CTH, CFH | HSD17B10 1909/4885TSHR 580/4885POLB 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.