Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23158046 | 1.00 | NOS1 (0.30) | NOS1 | |
| SCHEMBL21733403 | 0.82 | CASP3 (0.36) | NOS1 | |
| SCHEMBL21733378 | 0.82 | CASP3 (0.36) | NOS1 | |
| SCHEMBL24176145 | 0.82 | CASP3 (0.36) | NOS1 | |
| SCHEMBL10273862 | 0.82 | CASP3 (0.36) | NOS1 | |
| SCHEMBL23957329 | 0.82 | CASP3 (0.36) | NOS1 | |
| SCHEMBL22062833 | 0.78 | — | — | |
| SCHEMBL24854605 | 0.78 | PDK1 (0.33) | — | |
| SCHEMBL21216140 | 0.77 | ALDH1A1 (0.39) | — | |
| SCHEMBL24777810 | 0.77 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021057832-A1 | KRAS MUTANT PROTEIN INHIBITOR | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2021-04-01 | — | — | WO | disclosed |