Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.33 |
| ▸ | WNT3A | P56704 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314396 | 0.86 | MAPT (0.34) | MEN1CYP1A2CYP2C9KMT2AL3MBTL1 | |
| SCHEMBL2319689 | 0.86 | NOTUM (0.34) | MEN1KMT2AHTTMAPTSMN1; SMN2 | |
| SCHEMBL2322133 | 0.86 | ALDH1A1 (0.39) | L3MBTL1KDM4ECTNNB1WNT3AALDH1A1 | |
| SCHEMBL2314339 | 0.85 | PARP1 (0.38) | SLC6A2MEN1CYP1A2KMT2AKDM4E | |
| SCHEMBL2321527 | 0.85 | IMPDH2 (0.31) | — | |
| SCHEMBL2319253 | 0.84 | KDM4E (0.43) | HTR1ASLC6A2HTR2BSIGMAR1CYP1A2 | |
| SCHEMBL2320678 | 0.84 | MEN1 (0.33) | MEN1KMT2APKMHPGD | |
| SCHEMBL2316423 | 0.81 | BACE1 (0.38) | CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL2319041 | 0.79 | CYP3A4 (0.35) | HTR1ASLC6A2HTR2CHTR2BSIGMAR1 | |
| SCHEMBL2317591 | 0.77 | CYP3A4 (0.43) | HTR1ASLC6A2HTR2BSIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1609786-B1 | 5-alkenone-3,3-dimethyl-benzoxepines derivatives useful for the preparation of antidiabetic pentadienoic acids | MERCK SANTE SAS (FR) | 2011-08-03 | — | — | EP | claimed |